Page 179 - Physiology and Pathophysiology MNU 2024-2025 نظرى

Clinical pharmacy 2024/2025 Level 2 Pharm D Physiology and Pathophysiology (MD303)
4- Bar receptor reflex is activated to attempt to ↑ Pa to normal
Orthostatic hypotension
 Fainting on standing

➔ May occur in individuals whose Baroreceptor reflex
is impaired.

 E.g individuals treated with sympatholytic agents.

B) hemorrhage [ acute blood loss]
1- In blood volume➔ ↓ Pa

2- The baroreceptor reflex is activated ➔ ↑
Sympathetic, ↓Parasympathetic.

3- Arteriolar vasoconstriction & ↓capillary pressure
(Pc) ➔ ↑capillary absorption ➔ restore circulating

blood volume.
4- The rennin – Angiotensin system is activated due to
the decrease in renal perfusion blood volume.

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