Page 46 - phytochemistry general program
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Extraction and isolation of ipeca alkaloids
Quantitative determination of ipeca alkaloids
Emetine has been determined by volumetric, spectrophotometric and .1
In biological fluids emetine is determined through HPLC . .2
Pharmacology and uses
Liquid extract of ipeca and tincture are widely used as expectorant and as .1
emetic in case of poisoning. ( they have an irritant effect on the stomach ).
Emetine and 2, 3 (±) dehydroemetine DHE, are still the drugs of choice for .1
the treatment of severe acute amoebic intestinal infections, . .2
Emetine and DHE were proved to be cytotoxic and effective in leukemia.
Ipeca alkaloids are diaphoretic, alone or in combination with opium (e.g. .3
Dover's powder).
2- Curare alkaloids
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