Page 51 - phytochemistry general program
P. 51
Papaverine possesses spasmolytic (smooth muscle relaxant ) and .1
vasodilator activity. .2
It is used as antispasmodic for GIT spasms and in bronchial asthma in a
dose up to 600 mg of papaverine HCL daily.
C22H23NO7 41N3o.s4capine (Narcotine)
O
O NMe
MeO H
MeO H
O
Lactone ring MeO
O
Properties
It is a laevorotatory, very weakly basic alkaloid .1
Practically insoluble in water .2
Containing a lactone ring. .3
Hot alkali hydroxide opening of lactone ring. .4
Being a weak base, it can be extracted from aqueous acid solution with .5
chloroform.
Alkaloids of Opium phenylethylamine structure
Narceine
49
