Page 48 - phytochemistry general program

Tubocurarine can be quantitatively estimated either biologically or spectro- .4
photometrically.

1- Biological assay (head-drop method)

It is the smallest amount of the drug capable of producing a full head drop in
50% or more of
the test group.

2- Spectrophotometric assay:

Based on measuring the absorbance at max 280 nm.

Uses

Skeletal muscle relaxant.

- Used as adjuvant to anaesthesia to secure muscular relaxation in surgical
operations,

- Control and reduce convulsions of strychnine poisoning and tetanus

Opium alkaloids

Opium is the air-dried latex (of milky exudate) obtained by the incision .1
from the unripe capsule of Papaver somniferum (Papaveraceae).

It contains not less than 10% of morphine and not less than 2% of codeine. .2

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