Page 195 - Phytochemistry 2 (06-PG 605)

i- Psoralens

used in the treatment of virtiligo and psoraisis
Topical psoralens are useful for small lesions as well as inthe
treatment of children
oral psoralens are effective for treating multiple lesions.

liver function tests should be performed prior to initiating
therapy

Side effects
phototoxic reactions , prolonged PUVA (Psoralen plus
ultraviolet A ) treatment increases the risk of skin cancer(
squamous cell carcinoma).