Page 49 - Pharmaceutics III_ 02-06-01304_Fall 2025_ Pharm D_Electronic book

• Use of desiccant packets.
• Airtight containers.
• Avoid exposure to sunlight.

Tablet Stability Considerations:
1. Physical stability: color, hardness, disintegration.
2. Chemical stability: hydrolysis, oxidation, photolysis.
3. Microbiological stability: for moisture-prone tablets.

Preventive measures:
• Use of antioxidants, light-resistant containers.
• Control of moisture.
• Use of stabilizing excipients.

Examples of Common Tablets and Formulations:

Drug Type Key excipients Notes

Paracetamol Uncoated Starch, PVP, Mg stearate Analgesic/antipyretic

Aspirin Enteric-coated CAP, talc, lactose Avoid gastric irritation

Metformin Sustained release HPMC, MCC Extended action

Nitroglycerin Sublingual Lactose, PVP Rapid absorption

Vitamin C Chewable Mannitol, flavor Pleasant taste

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