Page 192 - Applied Pharmacognosy
P. 192

Detectors in HPLC

                   Electrochemical Detector (ED)

❑ ED responds to analytes that can be oxidized or reduced, such
   as phenols, aromatic amines, peroxides, ketones, aldehydes,
   aromatic halogen compounds, and aromatic nitro compounds.

❑ Ed requires a mobile phase that will conduct electricity.
❑ It is the most sensitive detector; LOD 10-12 g/ml.

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