Page 193 - Applied Pharmacognosy
P. 193

Detectors in HPLC

                   Electrochemical Detector (ED)

❑ The flow cell contains a working
   electrode (e.g. carbon paste) and a
   reference electrode (Ag-AgCl).

❑ The potential is maintained at a selected
   value with respect to the Ag|AgCl
   reference electrode, and current is
   measured between the working
   electrode and the stainless steel
   auxiliary electrode. Current is
   proportional to solute concentration.

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