Page 78 - Pharmaceutics IV (02-06-01305)

Parenterals: Containers & packaging

Container form: single-dose

• A single-dose container when opened, it cannot be resealed with
assurance that sterility has been maintained.

• Single-dose containers may be ampuls or single-dose vials or special
devices.

• Some single-dose preparations are to be administered in small
volumes (SVP) or large volume infusions (LVP, preservative-free).

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Parenterals: Containers & packaging

Container form: single-dose

Ampoules
• Glass ampoules are supplied as open necked

containers that are sealed by fusion of the
narrow glass neck after filling.
• Usually, the neck of the ampoule has a painted
ceramic ring on it, that acts as a weak point at
which the ampoule can be easily snapped
open by hand without breaking the body.

150

Salma E. EL-Habashy