Page 77 - Pharmaceutics IV (02-06-01305)
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Parenterals: Containers & packaging
Container material
Glass
• It must be clear and colorless or
light amber to permit inspection of
its contents.
• Glass types I, II, and III are
suitable for parenteral products, with
type I being the most resistant to
chemical deterioration.
147
Parenterals: Containers & packaging
Container material
Plastic
• Thermoplastic polymers have been established as packaging
materials for sterile preparations such as LVP, ophthalmic solutions,
and, increasingly, SVP.
• Three principal problem areas exist in using these materials:
1. Permeation
2. Leaching
3. Adsorption
148
Salma E. EL-Habashy 74
