Page 80 - Pharmaceutics IV (02-06-01305)

Parenterals: Containers & packaging

Container form: single-dose

Infusion bags and bottles
• LVP products are packaged in glass bottles (less common),

collapsible plastic bags and semi-rigid plastic bottles.
• Collapsible bag are the most common form. They are manufactured

from PVC (problems of plastic!) or more increasingly polyolefin plastic.
• Collapsible bags usually have an additive port to allow other injectable

drugs to be added to the infusion fluid.

153

Parenterals: Containers & packaging

Container form: multiple-dose

• A hermetic container that permits withdrawal of
successive portions of the contents (preservative!)
without changing the strength, quality, or purity of the
remaining portion.

• They are usually packaged in glass vials or cartridges
with a synthetic rubber septum (closure) held in place by
an aluminium seal around the neck of the glass vial.

154 77

Salma E. EL-Habashy