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Level two – Semester 4 - PharmD      Biochemistry-II PB-403 (Practical course)     2024/2025




                                        Aggregation of
                         RBCs                  RBCs             glomerulonephritis
                   Cellular                                       Pyelonephritis






                        WBCs            Aggregation of             (Urinary tract
                                              WBCs                infection in the
                                                                    renal pelvis)

                                                     III. Crystals

                     Crystal type             Shape             Condition                   picture


                     Calcium               Envelope-        Ethylene glycol
                  oxalate(Di-
                      hydrate)             like shape          poisoning







                                                               Diagnostic
                     Cystine               Hexagons
                                                             of cystinuria




                                                               Present in
                                                             alkaline urine
                 Magnesium
                  ammonium                 Resemble            e.g.: urine

                  phosphate                coffin lids      contain urease
                                                               producing

                                                                bacteria
                                Note: phosphate crystals are formed in alkaline urine.

                                              Wide
                                                              -Tumor lysis
                                           ranges of
                    Uric acid               sizes and          syndrome
                     (Urate)              shapes like          -Uric acid

                                           rhomboid
                                                            nephrolithiasis
                                           and plates                                   Rhomboid shape

                                     Note: urate crystals are formed in acidic urine.




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