Page 77 - Practical Handout bio 2 mnu 2025_Neat
P. 77

Level two – Semester 4 - PharmD      Biochemistry-II PB-403 (Practical course)     2024/2025


                       3.  Blood clotting:

                   Conversion  of  fibrinogen  to  insoluble fibrin is  essential  for  blood


                   clotting.






































                       4.  Transporter function:
                              General transport system:                  Specific transport system:


                       Albumin is a general carrier for many                 Name of       Substance

                                      substances:                             protein        or ions
                          Exogenous                Endogenous                                carried
                      substances (drugs)            substances           Ceruloplasmin      Copper

                        ❖  sulfa drugs            ❖  bilirubin             Transferrin        Iron
                        ❖  salicylates            ❖  fatty acids         Apolipoprotein      Lipid
                        ❖  barbiturates           ❖  hormones               Thyroxin

                        ❖  digoxin                ❖  ions                    binding       Thyroxin
                                                                             globulin
                                                                              (TBG)






                         Diagnostic value of plasma proteins:



                                                     Page 77 of 130
   72   73   74   75   76   77   78   79   80   81   82