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15.1 mmHg. 82.5% patients had no organ failure; patients had organ failure with 1 and ≥ 2

                  organs were 6% and 2.5%. The rates of SSC-3 obligation in blood culture; fluid resuscitation;
                  using broad spectrum  antibiotics and lactate measurement were sequentially 97.5%; 90%;

                  100% and 90% . The rate of overall SSC-3 obligation was 77.5%. 100% patients were collected

                  the personal information on HIS within 5 minutes; 90% cases were examined by doctors within

                  10 minutes; 77.5% patients were performed the medical presciptions by  nurses within 10

                  minutes. Medicine and medical devices were available for treatment within 10 minutes in 65%

                  cases, and not available for treatment within 15 minutes in 5% cases. The rate of positive blood
                  cuture  was  40%  cases;  2.5%  patients  needed  mechanical  ventilation.  80%  patients  were

                  discharged;  20%  patients  needed  transfering  to  other  hostipals.  The  median  length  of

                  hospitalization was 8 (6; 11.75) days.  The median ICU length of stay was 5.5 (3; 8) days.

                  There was no correlation between the SSC-3 obligation and general characteristics of patients;

                  sources of infection; the diagnoses; APACHE II score; SOFA score; the number of organs
                  underwent failure; the results and seveval related factors.

                        IV. CONCLUSIONS

                        The rate of overall SSC-3 obligation was 77.5%. The rates of SSC-3 obligation in using

                  broad spectrum antibiotics; blood culture; fluid resuscitation; and lactate measurement were

                  sequentially 100%; 97.5%; 90% and 90% . There were still 5% cases that medicine and medical
                  devices were not available for treatment within 15 minutes. Therefore, we suggest that the

                  Emergency Department should organize the human resource more effectively to focus on these

                  emergency cases.

                  TÀI LIỆU THAM KHẢO

                  1.  Acheampong,  A.  and  J.L. Vincent,  A  positive  fluid  balance  is  an  independent  prognostic  factor  in
                  patients with sepsis. Crit Care, 2015. 19(1): p. 251.
                  2.  Angus, D.C., et al., Epidemiology of severe sepsis in the United States: analysis of incidence, outcome,
                  and associated costs of care. Crit Care Med, 2001. 29(7): p. 1303-10.
                  3.  Annane,  D.,  et  al.,  Corticosteroids  in  the  treatment  of  severe  sepsis  and  septic  shock  in  adults:  a
                  systematic review. Jama, 2009. 301(22): p. 2362-75.
                  4.  Annane, D., et al., Effect of treatment with low doses of hydrocortisone and fludrocortisone on mortality
                  in patients with septic shock. Jama, 2002. 288(7): p. 862-71.
                  5.  Bochud, P.Y., et al., Antimicrobial therapy for patients with severe sepsis and septic shock: an evidence-
                  based review. Crit Care Med, 2004. 32(11 Suppl): p. S495-512.


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