Page 594 - Atlas of Small Animal CT and MRI
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5.8




             Urinary tract


















             Introduction                                       quantify renal volume with good accuracy.  Contrast‐
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                                                                enhanced MR urography gives excellent information on
             The urinary tract is frequently evaluated with CT   renal anatomy and function, but it is less commonly
             because of its excellent spatial resolution for examining   used.
             small structures, such as ureters or small calculi. The   Contrast‐induced nephropathy (CIN) has been
             function of each kidney can also be subjectively  evaluated   described in people, which results in acute kidney injury,
             by evaluation of the renal and urine enhancement with   causing an increase of creatinine of more than 0.5 mg/dl
             contrast medium. Quantitative functional analysis has   or 25% over baseline within 48 hours of contrast
             also been investigated using dynamic CT and perfusion     administration.  This has not been fully characterized in
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             techniques. 1,2                                    dogs and cats; however, similar risk factors and preven-
               The kidneys, ureters, bladder, and urethra can be   tion measures can be extrapolated. Hypovolemia, exist-
             imaged with CT and MR (Figures  5.8.1, 5.8.2). Renal   ing renal dysfunction, nephrotoxic drugs, hypotension,
               contrast enhancement is multiphasic as contrast medium   heart failure, and diabetes are risk factors for
             is filtered by the urinary system (Figure 5.8.3). The cortex   CIN. The use of iso‐ and low‐osmolar contrast medium
             enhances to a greater degree than the medulla on the   decreases risk of CIN, as does pre‐ and postcontrast
               initial corticomedullary phase. The nephrogram phase   hydration with intravenous saline. 7
             shows uniform renal enhancement prior to urine
               collecting in the renal pelvis. The renal pelvis and medulla   Developmental disorders
             are enhanced during the excretory phase. The ureters fill
             segmentally with contrast medium as a result of peristal-  Renal cysts
             tic contractions during the excretory phase. The ureters   Autosomal dominant polycystic kidney disease results
             enter the dorsal bladder wall near the trigone. The  urethra   in progressive development and enlargement of
             is less commonly evaluated with cross‐sectional imaging   low‐attenuation cysts in the renal cortex in cats. The
             but is easily included by scanning through the pelvis, and     disease has also been reported in dogs. In adult animals,
             CT urethrography can be performed to better delineate   the origin of cysts, whether congenital or degenerative,
             the urethral lumen.                                may be undetermined. Cysts may deform the capsule
               CT angiography is used to evaluate the anatomy of   and distort the renal pelvis and are best seen on contrast‐
             the renal vasculature, which is advantageous for surgical   enhanced  images (Figure  5.8.4).   Solid  tumors  and/or
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             planning.  There is normally one artery and one vein   replacement of renal tissue with cystic structures occurs
                     3,4
             supplying each kidney; however, anatomic variants of   in hereditary multifocal renal cystadenocarcinomas in
             additional arteries and veins occur frequently in cats.    German Shepherd Dogs, along with nodular
                                                           4
             MR angiography of the canine renal vasculature has also     dermatofibrosis and uterine neoplasia.  These cysts
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             been described.  CT software applications can be used to   often have attenuation greater than 5 HU, presumably as
                          5
             Atlas of Small Animal CT and MRI, First Edition. Erik R. Wisner and Allison L. Zwingenberger.
             © 2015 John Wiley & Sons, Inc. Published 2015 by John Wiley & Sons, Inc.
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