Page 1026 - The Toxicology of Fishes

1006 The Toxicology of Fishes

anabolic steroids, 470 antimicrobials, 79, 494, 603
analysis of variance (ANOVA), 676–677, 739, 746 antimony, 781
α-naphthoflavone (ANF), 541, 544 antimycin, 299, 673
anatoxins, 444, 445 antioxidant defense systems, 274, 278–286, 300,
androgen receptors, 257, 463, 465, 470 440, 607, 619
androgens, 257, 460, 461, 465, 469, 470, 472, 473 enzyme, 278–283, 301–302
androstenedione, 188 nonenzymatic, 303
anemia, 829, 830 antioxidant enzymes, 693–694, 712, 798
anemones, 444 antioxidant response element (ARE), 189, 198,
anesthesia, 78, 182, 206, 429 281, 283, 287, 288, 301, 693
vs. stunning, 700 -mediated gene regulation, 288–291
angiotensin, 88, 557 antioxidants, 213, 258, 286, 287, 288, 291, 292,
Anguilla sp.; see also specific types of eels 298, 304, 305, 371, 468
A. anguilla, 547, 558, 974 low-molecular-weight, 283–286
A. japonica, 560 AOX, 357, 358, 954, 957
A. rostrata, 444 Aphanizomenon, 444
aniline, 207, 430 Aplodinotus grunniens, 43
anionic detergent uptake, 76 apolipoproteins, 357, 358
anions, 88, 199, 201, 205, 300, 360 apoptosis, 287, 294, 403, 407, 409, 439, 440, 441,
tubular, secretion of, 88–89 442, 491, 507, 607, 691, 831, 832
anisoles, 65, 76 apparent volume of distribution, 97, 100
Anoplarchus purpurescens, 365–366 application factors (AFs), 677
anterior kidney, 491–492 aquatic systems
anterior pituitary, 458 as chemical repositories, 3–4
anterior–posterior axis, 419 chemical bioavailability in, 9–45
anthracene, 91, 168, 650, 652–653, 654 design of, for research, 733–747
anthracyclines, 361 management of, 958
2-anthramine, 572 modeling in, 645–657
anthrene bioconcentration factor, 654 pulp mill effluent effects on, 951
anthropogenic chemicals, 11 arachidonic acid, 164, 167, 168, 179, 287, 351,
antiandrogens, 472 461, 463
antibacterials, 296 epoxygenases, 167
(+)-anti-benzo(a)pyrene-7,8-dihydrodiol-9,10- hydrolases, 167
oxide, 180, 194, 207, 209 Arctic char (Salvelinus alpinus), 173, 208
antibiotics, 73, 79, 85, 188, 296, 299 arctic grayling (Thymallus arcticus), 78, 120
antibodies, 622 Arctopsyche grandis, 794
constitutive androstane receptor (CAR), 166 arene oxides, 180, 190
CYP1A, 162 arginine, 294
CYP1B1, 163 oxidation of, 276
CYP2B1, 164 arginine vasotocin, 88
CYP2E1, 166 Aristichthys nobilis, 74
CYP2K1, 168 ARNT, 615
CYP2M1, 168 ARNT1, 250, 256, 828, 833
CYP3A, 169 ARNT2, 250, 256, 828
flavin-containing monooxygenase, 176 ARNT2X, 251
P450B, 164 Arochlor 1242, 856
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porcine FMO1, 177 Arochlor 1254, 214, 369, 468, 509, 563, 566, 567
protein-specific, 688 aromatase, 460, 470, 990
antibody-forming cells (AFCs), 492, 498, 504, aromatic aldehydes, 179
505, 509, 511 aromatic amines, 179, 538, 538–539
antifungals, 163, 175 aromatic amino acids, 206
antigen presenting cells (APCs), 496 aromatic carbon hydroxylation, 157
antigens, 493, 495, 496, 509 aromatic halides, 190