Page 1041 - The Toxicology of Fishes

Index 1021

trans-dihydrodiols, 180 dissolved organic carbon (DOC), 12, 35, 39, 40,
dihydropyridium ion, 426 42, 128, 131
17,20β-dihydroxy-4-pregnen-3-one (17,20β-P), mercury accumulation, and, 38
461, 465 dissolved organic matter, 67, 111, 115, 647, 810
(+)-7β,8α-dihydroxy-9α,10α-oxy-7,8,9,10- dissolved oxygen, 67–68, 703
tetrahydrobenzo(a)pyrene (BPDE), 196 dissolved solids, 60
7,8-dihydroxy-9,10-epoxy-7,8,9,10-tetrahydro- dissolved vs. suspended, 647
benzo(a)pyrene (BPDE), 541 Dissostichus mawsoni, 341
diiodotyrosine (DIT), 477 distal tubule, 88
diketones, 427 distribution, xenobiotic, 56, 57, 60, 63, 77–82, 96,
dimerization, 464, 477 106
dimethyl formamide (DMF), 673 disulfides, 294
dimethyl sulfoxide (DMSO), 673 divalent cationic metals, 13
dimethylaminobenzene, 538 diversity indices, 745
N,N-dimethylanaline (DMA), 176 diverticula, 69
7,12-dimethylbenzanthracene (DMBA), 163, 190, blind, 16
510–512, 538, 539, 540–541, 543–544, DMBA-3,4-dihydrodiol, 544
551, 563, 569, 572 DMBA-3,4-diol-1,2-oxide, 540
–DNA adducts, 543, 544, 552–553 DNA, 275, 696–700
dimethylmercury, 36 adducts, see DNA adducts
dimethylnitrosamine (DMN), 572, 574 alkylation, 200
2,6-dimethylnitrosomorpholine, 572 binding, 357, 463, 563
2,4-dimethylphenol, 430 binding domain, 353, 464, 558
dimethylphosphorothioates, 352 binding protein, 160
m-dinitrobenzene, 179 carcinogenic alteration of, 542–549
dinoflagellates, 443, 444 damage, 305, 307, 563, 574, 577, 607
diol epoxides, 192 oxidative, 544–547
dioxin, 41, 329, 350, 472, 507–508, 509, 600, 604, ultraviolet radiation and, 300
605, 611, 613, 614, 624, 699, 859, 889, 897 metabolism, 441
congeners, 944 repair, 539, 546, 549–553, 561, 570, 574
in pulp mill effluent, 934, 937, 947, 957 response elements, 472
toxicity, mechanisms of, 827–828 single-strand breaks, 699
dioxin-like compounds, 253, 601, 602–603, 604, DNA adducts, 163, 208, 209, 211, 235, 369, 539,
605, 617, 618, 623, 624, 625, 627, 819–861 542, 543, 544, 552–553, 562, 566, 567, 570,
tolerance to, 611–616 614, 688, 694, 695, 698, 699, 709, 885,
dioxin response elements (DREs), 160, 253, 827 887–889, 890, 891, 893, 895, 903, 907
dioxygen, 274, 350; see also O 2 hepatic, 887, 907
diphenols, 298 DNA-alkyltransferases, 549
diphosphate glucuronosyl dehydrogenase, 338 DNA polymerase II, 464
dipterans, benthic, 38 dodecyl sodium sulfate, 673
diquat, 297 dogfish shark, 106, 120, 206
direct repeats (DRx), 353 Scyliorhinus canicula, c-mos in, 558
direct reversal, 549 Squalus acanthias, see spiny dogfish shark
discharge requirements, 760 Dolly Varden char (Salvelinus malma), 82
disinfectants, 275 dominance, 428
dispersion train, 783 dopamine, 201, 204, 277, 283, 295, 421, 424, 443,
dissociation 458
coefficient, acid (K ), 12, 21, 24 luteinizing hormone secretion, and, 462
a
pH, and, 12 dopamine receptors, 441
constant, see pK a dopamine-β-hydroxylase, 283
constant, equilibrium (K ), 240, 241, 242, Dorosoma cepedianum, 43, 163, 548, 561, 744;
D
244, 245, 247 see also gizzard shad
rate constant, 240, 247 dorsal–ventral axis, 419