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1026 The Toxicology of Fishes
estrone-3-sulfate, 361 effects, 927–929
ethacrynic acid (ETHA), 193–194, 195 measures of, 19–20
ethanes, 113, 441 metabolism, and, 19
chlorinated, 16 persistent, 600
ethanol, 168, 178, 296, 439–440 potential, 927, 928
ethinylestradiol, 173, 985, 986, 987, 992, 994 pulse, 799
ethofenprox, 808, 815 regimes, complicated, 568
ethoxycoumarin O-deethylase, 169 –response assessment, 760, 762–763, 906,
ethoxyquin, 198, 213 907
ethoxyresorufin, 689 –response curves, 766, 768
ethoxyresorufin-O-deethylase (EROD), 160, 162, routes, 10, 11, 13, 16, 110–117, 663
163, 188, 208, 351, 375, 376, 377, 511, 605, CYP1A, and, 351
611, 614, 617, 689, 837, 839, 846, 857, 886, time frame, 10
889 water, 14–15, 16, 100–102, 122
ethylene, 441 expoxide hydrolase, 180–182
ethylenedibromide, 196 expressed sequence tags (ESTs), 184
PBTK model for, 121 extracellular superoxide dismutase (ECSOD),
ethylguanine, 567 278, 279, 288
ethylmercury, 442 extraction, renal, 95
ethylmorphine, 164 extrapolation, 762–763, 766, 767, 771, 772
ethynylestradiol, 11 extravascular spaces, 108, 109
eukaryotes, 288 Exxon Valdez, 6, 557, 695, 703, 886, 897,
gene expression in, 287 925–930
European eel (Anguilla anguilla) damage assessment, 926
ceruloplasmin in, 286 response to, 925–926
ras gene in, 558 eye tumors, 559, 560
European flounder, lysosomal alterations in, 373 eyes, fish, 423, 427, 440, 443, 466
eutrophication, 945
everted repeats (ERx), 353 F
excision repair, 549–550, 551, 698 FADH , 277
2
excretion, 92, 154, 184, 212, 330, 349 farnesol X receptor (FXR), 353, 356, 358, 363
acetylation, and, 207 fasting, 168
branchial, 82–83, 133 fate, see chemical: fate
dermal, 90–91 fathead minnow (Pimephales promelas), 74, 76,
urinary, 58, 86–90, 92, 105, 106, 117, 120, 113, 117, 119, 348, 674, 734
183, 352 acclimation, 611
xenobiotic, 56, 57, 58, 62, 75, 85 cadmium, and, 735
exercise, blood flow patterns, and, 78 copper, and, 29, 30, 33
exfoliation, of intestinal cells, 83 17β-estradiol, and, 986
exocrine pancreatic cells, 331, 335 ethinylestradiol, and, 987
exogenous compounds, 183, 330, 359 fenvalerate, and, 808, 809, 813
expected environmental concentration (EEC), freshwater test, 950
758–759 HSP70 expression in, 691
exposure HSP90 induction in, 691
actual, 927, 928 insecticides, and, 433
assessment, 645–657, 662, 762, 902 lead, and, 443
biomarkers of, 685, 687, 694, 696, 698 life-cycle test, 950–951
characterization, 762 narcotics, and, 430
chronic, 799, 806 nickel toxicity, 31
vs. acute, 708 nonylphenol, and, 990, 991
concentration, 20 nuptial tubercles in, 470
dietary, 13, 16–19, 848 steroid hormones in, 848
TCDD, 831 strychnine, and, 445