Page 1046 - The Toxicology of Fishes
P. 1046

1026                                                       The Toxicology of Fishes


                       estrone-3-sulfate, 361                       effects, 927–929
                       ethacrynic acid (ETHA), 193–194, 195         measures of, 19–20
                       ethanes, 113, 441                            metabolism, and, 19
                          chlorinated, 16                           persistent, 600
                       ethanol, 168, 178, 296, 439–440              potential, 927, 928
                       ethinylestradiol, 173, 985, 986, 987, 992, 994  pulse, 799
                       ethofenprox, 808, 815                        regimes, complicated, 568
                       ethoxycoumarin O-deethylase, 169             –response assessment, 760, 762–763, 906,
                       ethoxyquin, 198, 213                             907
                       ethoxyresorufin, 689                         –response curves, 766, 768
                       ethoxyresorufin-O-deethylase (EROD), 160, 162,   routes, 10, 11, 13, 16, 110–117, 663
                           163, 188, 208, 351, 375, 376, 377, 511, 605,   CYP1A, and, 351
                           611, 614, 617, 689, 837, 839, 846, 857, 886,   time frame, 10
                           889                                      water, 14–15, 16, 100–102, 122
                       ethylene, 441                            expoxide hydrolase, 180–182
                       ethylenedibromide, 196                   expressed sequence tags (ESTs), 184
                          PBTK model for, 121                   extracellular superoxide dismutase (ECSOD),
                       ethylguanine, 567                             278, 279, 288
                       ethylmercury, 442                        extraction, renal, 95
                       ethylmorphine, 164                       extrapolation, 762–763, 766, 767, 771, 772
                       ethynylestradiol, 11                     extravascular spaces, 108, 109
                       eukaryotes, 288                          Exxon Valdez, 6, 557, 695, 703, 886, 897,
                          gene expression in, 287                    925–930
                       European eel (Anguilla anguilla)             damage assessment, 926
                          ceruloplasmin in, 286                     response to, 925–926
                          ras gene in, 558                      eye tumors, 559, 560
                       European flounder, lysosomal alterations in, 373  eyes, fish, 423, 427, 440, 443, 466
                       eutrophication, 945
                       everted repeats (ERx), 353               F
                       excision repair, 549–550, 551, 698       FADH , 277
                                                                     2
                       excretion, 92, 154, 184, 212, 330, 349   farnesol X receptor (FXR), 353, 356, 358, 363
                          acetylation, and, 207                 fasting, 168
                          branchial, 82–83, 133                 fate, see chemical: fate
                          dermal, 90–91                         fathead minnow (Pimephales promelas), 74, 76,
                          urinary, 58, 86–90, 92, 105, 106, 117, 120,   113, 117, 119, 348, 674, 734
                               183, 352                             acclimation, 611
                          xenobiotic, 56, 57, 58, 62, 75, 85        cadmium, and, 735
                       exercise, blood flow patterns, and, 78       copper, and, 29, 30, 33
                       exfoliation, of intestinal cells, 83         17β-estradiol, and, 986
                       exocrine pancreatic cells, 331, 335          ethinylestradiol, and, 987
                       exogenous compounds, 183, 330, 359           fenvalerate, and, 808, 809, 813
                       expected environmental concentration (EEC),   freshwater test, 950
                           758–759                                  HSP70 expression in, 691
                       exposure                                     HSP90 induction in, 691
                          actual, 927, 928                          insecticides, and, 433
                          assessment, 645–657, 662, 762, 902        lead, and, 443
                          biomarkers of, 685, 687, 694, 696, 698    life-cycle test, 950–951
                          characterization, 762                     narcotics, and, 430
                          chronic, 799, 806                         nickel toxicity, 31
                              vs. acute, 708                        nonylphenol, and, 990, 991
                          concentration, 20                         nuptial tubercles in, 470
                          dietary, 13, 16–19, 848                   steroid hormones in, 848
                              TCDD, 831                             strychnine, and, 445
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