Page 1237 - Veterinary Toxicology, Basic and Clinical Principles, 3rd Edition

1168 Index

VetBooks.ir Cannabinoid(s), 387 388 cellular defense against DNA damage, Carryover of feed of coccidiostats and
chemical carcinogenesis, 339 348
medicated feed, 111 113
multistep biological process, 342 344
receptors, 389
Cartilage degeneration, 367
Cannabis indica (C. indica), 388
347 348
Cannabis sativa (C. sativa), 387, 896
Cassava, 937
Cantharidin, 236, 786 DNA repair mechanisms, 347f “Cascade” system, 127, 128t
Capacitation of spermatozoa, 290 epigenetic basis, 351 352 Castor bean (Ricinus communis), 54, 63 64,
CAPAE-Ouest. See College of Veterinary function of age and multistage model, 344 891, 903
Medicine of Nantes (CAPAE-Ouest) genetic basis, 348 350 Catechol-O-methyltransferase (COMT), 202
Capillary electrophoresis (CE), 164 genotoxicity, mutagenicity, and Catecholamine, 200
CAR. See Constitutive androstane receptor carcinogenicity tests, 353t neurotransmitters, 202 203
(CAR) mode of action of chemical carcinogens, Catha edulis (C. edulis), 395, 400 401
Carassius auratus. See Goldfish (Carassius 344 346 Catharanthus rosea (C. rosea), 199
auratus) oncogenes, 348 350 Cathartics, 379 381, 392, 907, 1147 1148
Carbachol (CB), 683 radiation, 350 351 therapies, 597
CB1 receptors, 389 terminology, 339 Cats, 40, 784
CB2 receptors, 389 tumor suppressor genes, 348 350 adverse effects of methocarbamol, 1155
Carbamates (CMs), 51, 200 201, 234, Carcinogenic compounds regulation, 95 96 amitraz poisoning in, 525, 527 528
495 496, 496f, 501f, 563 Carcinogenic risk assessment, 95 96 fipronil poisoning in, 533
active site gorge of AChE, 503f Carcinogenicity, 1022 fipronil toxicity in, 536
chronic toxicity, 505 506 tests, 149, 353t Cattle, 268 269, 668, 670 671, 850 851,
compound, 495 Carcinogens 858, 902, 932, 941, 944
insecticides, 723 assays for, 352 353 clinical signs of monensin toxicosis, 1082
interaction of ACh (I), carbamate carbaryl classification, 352, 352t fumonisin toxicity in, 1014 1015
(II), and organophosphate chlorpyrifos- Carcinoma(s), 339. See also Cancer graze sheep before, 851
oxon, 503f Cardenolides, steroidal glycosidic, 880 grazing, 855 856
mechanism of action, 501 503 Cardiac iron toxicity in, 435
pesticides, 502t activity, 908 onset of salivation, 1029
pharmacokinetics, 496 501 dysfunction, 224 toxicology of sulfur dioxide, 668 669
toxicity, 504 failure, 74 Cattlyst. See Laidlomycin
treatment of acute poisoning, 505 pathology of petroleum, 666 Causation
Carbamic acid, 563 phytochemicals affecting cardiac system, general, 186 187
derivative fungicides, 570 228 specific, 187 188
derivatives, 573, 576 plants containing cardiac glycosides, 1152t Caveolae, 1005
Carbaryl, 495 496, 501f, 502t syndrome, 882 CB. See Carbachol (CB)
Carbendazim, 576 577 Cardioactive glycosides, 891 892 CBC. See Complete blood count (CBC)
Carbinoxamine, 376, 376t Cardiotoxicity, 227, 949 950 CBER. See Center for Biologics Evaluation
Carbocations, 344 Cardiotoxins, 235 236 and Research (CBER)
Carbofuran, 496, 501f, 502t Cardiovascular dysfunction, 1006 CCL. See US EPA Contaminant Candidate List
Carbohydrates, 759 Cardiovascular system (CCL)
Carbon dioxide (CO 2 ), 216 218, 378 379 mercury toxicity, 459 CCME. See Canadian Council of Ministers of
Carbon monoxide (CO), 217, 219, 629, 711, monensin effect, 1075 the Environment (CCME)
728 serotonin effect, 1151 CCREM. See Canadian Council of Resource
clinical presentation, 634 635 toxic chemical distribution, 134 and Environment Ministers (CCREM)
diagnostic testing, 635 Cardiovascular toxicity CCRVDF. See Codex Committee on Residues
pathophysiology, 634 alkaloid-containing plants, 230 232, 231t of Veterinary Drugs in Food
postmortem findings, 635 ancillary causes of cardiac toxicity, 235 (CCRVDF)
prevention, 635 cardiotoxicity, 227 CCT. See Chest computerized tomography
prognosis, 635 cyanide-containing plants, 230 (CCT)
sources of exposure, 633 fertilizers, 233 234 CDER. See Center for Drug Evaluation and
toxic dose, 633 634 glycoside-containing plants, 228 230, 229t Research (CDER)
toxicokinetics and toxicodynamics, 634 herbicides, 234 cDNA. See Complementary DNA (cDNA)
treatment, 635 hymenoptera, 235 CDRH. See Center for Devices and
vulnerable populations, 634 insecticides, 234 235 Radiological Health (CDRH)
Carbon nanotubes, 322 ionophores, 233 CE. See Capillary electrophoresis (CE)
Carbon tetrachloride (CCl 4 ), 246 metal-induced cardiac toxicity, 233 Cell
metabolism and mechanism of toxicity, 251f mycotoxins, 235 adhesion proteins, 155
Carbonium ions, 344 nitrate-containing plants, 233 cell-specific markers of toxicity, 156 157
Carbonyl chloride (CCl 2 O), 73 ophidian, 235 236 genomic analysis, 156 157
Carbosulfan, 496, 502t oxalate-containing plants, 232 233 proteomic analysis, 156
Carboxyhemoglobin (COHb), 219, 633 634 pesticides, 234 235 cell-specific reproductive toxicants, 299,
Carboxylic ionophores, 1073, 1074f, phytochemicals affecting cardiac system, 303 304
1077 1078 228 culture system types, 151 153, 151f, 154t
Carcinogenesis, 108 111, 339, 1046 plant-induced cardiotoxicity, 227 228 culture/ELISA assay, 599
agents causing, 339 351 Carrion-contaminated feed, 746 747 death, 246 247