Page 1238 - Veterinary Toxicology, Basic and Clinical Principles, 3rd Edition

Index 1169

VetBooks.ir growth and proliferation, 155 Central peripheral distal axonopathy, 199 role of environmental estrogens in diseases,
toxicity of fipronil desulfinyl, 535
tremorgenic effects, 1033 1035
membrane damage, 246
811 813
disruption, 251
SERMs, 810 811
morphology, 155
as selective ER modulators, 808 809
Central vein, 242
cell shape, 155 Central peripheral proximal axonopathy, 199 xenoestrogens and phytoestrogens
cell volume, 155 Centrilobular necrosis, 247 as SERMs, 809 810
growth patterns, 155 Centruroides spp. See Bark scorpions Chemical-linked food safety, 733
membrane integrity, 155 (Centruroides spp.) Chemistry, Manufacturing, and Controls
proliferation, 222, 826 Cephalothorax, 784 (CMC), 92
shape, 155 Ceramide synthase, 1005 Chemotherapy, 329
viability, 154 Cereal grains, 305, 995 996 Chernobyl disaster, 333
volume, 155 Cerebrocortical necrosis, 573 574 Chernobyl Exclusion Zone (CEZ), 332 333
Cellular defense against DNA damage, Cerebrospinal fluid (CSF), 200 Chernobyl NPP accident (1986), 328 329,
347 348 Cerebrospinal meningitis, 1011 333, 351
Cellular excitation, 197 198 Certirizine, 376, 376t ChEs. See Cholinesterases (ChEs)
Cellular necrosis and apoptosis, 266 267 Cesamet. See Nabilone Chest computerized tomography (CCT), 641
Cellular oncogenes, 348 350 Cesium 137 ( 137 Cs), 328 Chest radiographs, 641
activation and inactivation, 349 Cesium absorption, 330 Cheyne Stokes respiratory pattern, 782
encoding protein products, 349 Cevanines, 877 CHF. See Congestive heart failure (CHF)
viral carcinogenesis, 349 350 CEZ. See Chernobyl Exclusion Zone (CEZ) Chickens, anticoagulant rodenticide toxicosis,
Cellular proto-oncogene (c-onc), 350, 350f CFR. See Code of Federal Regulations 594
Cellular respiration process, 621 (CFR) Chloramphenicol, 107, 363, 364t
Centaurea repens (C. repens), 884 CFSAN. See Center for Food Safety and Chlorcyclizine, 376, 376t
Centaurea spp. See Knapweeds (Centaurea Applied Nutrition (CFSAN) Chlordane, 510, 510f
spp.) CG. See Cyanogenic glycosides (CG) Chloride (Cl), 479
Center for Biologics Evaluation and Research cGMP, 180, 221 channels, 208
2
(CBER), 90 CH 3 CH(OH)CH 3 . See Isopropyl alcohol (IPA) Chloride ion (Cl ), 735
Center for Devices and Radiological Health Chalcogenides, 483 Chlorinated compounds, 509
(CDRH), 90 Chambered tuber, 859 Chlorinated hydrocarbons, 509 510
Center for Drug Evaluation and Research Chandelier Plant, 230 Chlorinated pesticides, 691
(CDER), 90 Charcoal as “universal antidote”, 906 Chlorine dioxide, 736
Center for Food Safety and Applied Nutrition CHCl 2 NO. See Phosgene oxime (CHCl 2 NO) Chlorine gas (Cl 2 gas), 71 73, 218, 509, 736.
(CFSAN), 90 Chelation, 79 See also Mustard gas (C 4 H 8 Cl 2 S)
Center for Tobacco Products (CTP), 90 therapy, 440, 491 effects of exposure levels, 72t
Center for Veterinary Biologics (CVB), 91 Chelators, 82, 460 mechanism of action, 72
Center for Veterinary Medicine (CVM), 90 91 Chemical agents, 71 pharmacokinetics/toxicokinetics, 72
“CVM Updates”, 99 Chemical carcinogenesis, 339 348 toxicity, 72
pharmacovigilance program, 96 99 and dose-response, 341 342 treatment, 72 73
ADE, 97 Chemical carcinogens, 340 342, 340t 3-Chloro-4-methylbenzenamine hydrochloride,
adverse drug experience reporting, 97 genotoxic carcinogens, 340 724
safety signal detection, 98 99 mode of action, 344 346 Chloro-S-triazines, 561
unapproved drugs and veterinary devices, genotoxic carcinogens, 344 346 Chloroalkylthiodicarboximides, 575 576
97 98 in nature, 339 340 2-Chlorobenzalmalononitrile (CS), 1047
Centipedes, 785 786 nongenotoxic carcinogens, 340 341 6-Chloronicotinic acid, 521 522
Central nervous system (CNS), 149 Chemical Industry Institute of Toxicology Chlorophacinone, 586 587
alcohols and glycols effect, 647 (CIIT), 8 toxicity in target species, 590
amitraz effect, 526 Chemical terrorism, 71 Chlorophyll, 872
bee stings effect, 790 C 2 H 2 AsCl 3 ,77 79 Chlorophyllum molybdites (C. molybdites), 963
carbon monoxide effect, 634 635 CHCl 2 NO, 79 80 Chlorothalonil, 569 570, 575
CNS gonadal axis, 827 Cl 2 gas, 71 73 fungicide, 572 573
depressants, 386 387, 394 395 cyanide and HCN, 80 82 Chlorpheniramine, 376, 376t
flunitrazepam, 394 military nerve agents, 82 85 Chlorpyrifos, 496, 500f, 503
GHB, 394 395 mustard gas, 74 77 Chocolate, 40, 1145
depression, 650 phosgene, 73 74 Cholangiocarcinomata, 249
effects of nerve agents, 83 Chemical warfare agents, 71 Cholangiodestructive cholestasis, 252
glyphosate effect, 560 Chemical weapons, 71 Cholecalciferol, 616 617, 617f, 1156
Hg effects, 457 Chemical weapons of mass destruction mechanism of action, 617
ibotenic acid effect, 961 (CWMD), 496 toxicity, 617
imidacloprid effect, 521 522 Chemical-induced estrogenicity, 805 toxicokinetics, 617
metallic fungicides, 575 estrogenic chemicals of concern, 805 807 treatment, 617
MLs, 542 estrogens as risk factors for male Cholestanes, 877
nux-vomica/strychnine in, 613 reproductive tract problems, 813 814 Cholestasis, 252
phytoestrogens effect, 817 mechanisms of estrogen-induced Cholestatic
THC effect, 896 transactivation, 805 807 agonist, 1029 1030