Page 578 - Veterinary Toxicology, Basic and Clinical Principles, 3rd Edition
P. 578

mo;
                                     ,4
                                     calves
                              Comments/References
                                     for
                                       (2009)
                                     recommended
                                       al.
                                       et
                                       Lanusse
                                     Not
                              Unless
                              MTD
                              or
                                 Stated)
                              (LOEL
                                     SC
                              Dose
                                     mg/kg,
                                 Otherwise
                              Toxic
                                     2 8
                                          mg/kg/d 3 12  (2001) Breckenridge  and  Stevens  (1994) a  Extoxnet  LD 50 )  (PO,  mg/kg  14 80  (2001) Breckenridge  and  Stevens  PO mg/kg/day,  0.075  PO mg/kg/day,  (2001) Breckenridge  and  Stevens mg/kg/day 3 18  (2001) Breckenridge  and  Stevens  PO mg/kg/day,  2  PO mg/kg/day,  (1994) a  Extoxnet  LD 50 )  (PO,  mg/kg  11  (2001) Breckenridge  and  Stevens mg/kg/d 3 53  PO  (2001) Breckenridge  and  Stevens  PO mg/kg/day  2.0  PO mg/kg/day,  (2010) b  Fowler  (2009)  al.  et  Lanusse  SC 3 3d  mg/kg,  (1997) c  FDA  (2009)  al.  et Lanusse  SC  mg/kg,  (2010) d  INCH
                         Endectocides  NOAEL  0.25  PO  mo,  0.05  4 8  PO  mo,  1  1.5 2  weeks,  1.6  2.5  0.6  2  0.25  mg/kg,  3  0.6  2.5  1  PO  5  PO
                         Lactone  Dose  SC                                     SC  IM,  SC  IM,  Topical  SC  SC  IM,  SC  IM,  mg/kg  IM  q  PO  SC  IM,  topical  topical  topical  topical  topical
                         Macrocyclic  Therapeutic  (Route)  mg/kg,  0.2  N/A  N/A  N/A  N/A  mg/kg  0.2  mg/kg  0.2  mg/kg,  0.5  mg/kg,  0.2  N/A  N/A  mg/kg  0.2  0.2 0.5  mg/kg  0.3  mg/kg  0.2  h 3 4d,  24  mg/kg  0.2  mg/kg,  0.5  mg/kg,  0.5  N/A  mg/kg,  0.5  mg/kg,  1  N/A  N/A  mg/kg,  0.5




                         Various                  (CF-1,  (CD-I)                       (breeding)



                         of   Species     (beagle)  Mouse  pregnant)  Mouse  (pregnant)  (SD)  (SD,  pregnant)  Camelids  (beagle)  (collie)  Camelids  Horses
                         Toxicity    Cattle  Dog  Mouse     Rabbit  Rat  Rat  Rat  Cattle  Cattle  Dogs  Dogs  Goats  Lions  Pigs  Rats  Sheep  Cattle  Dogs  Goats  Mice  Rats  Sheep



                         43.2

                         TABLE  VetBooks.ir  Agent  Abamectin                  Doramectin                      Eprinomectin
   573   574   575   576   577   578   579   580   581   582   583