Page 579 - Veterinary Toxicology, Basic and Clinical Principles, 3rd Edition

(Continued )

mo;
,4 (2001) (2001) (2001) (2001) (2001) (2001) (1997) f (1997) f
calves for (2012) EMEA EMEA (2009) k (2007) l
Comments/References recommended Not (2009) al. et Lanusse Breckenridge and Stevens (1994) a Extoxnet Breckenridge and Stevens Breckenridge and Stevens Breckenridge and Stevens (1994) a Extoxnet Breckenridge and Stevens Breckenridge and Stevens (2010) b Fowler (2009) al. et Lanusse (1997) c FDA (2009) al. et Lanusse (2010) d INCHEM (2010) d INCHEM (2006) e Pfizer Caldwell and Lobetti (2009); al. et Lanusse (2000) g al. et Oege (2009); al. et Lanusse (2007) h al. et Plant (2009) al. et Lanusse (1996) i EMEA (2008) j al.

Unless IP IP

MTD mg/kg, mg/kg,

or LD 50 ) PO PO d, 35 35
(LOEL Stated) SC (PO, PO LD 50 ) PO PO IM (LD 50 ), (LD 50 ),

Dose mg/kg, mg/kg mg/kg/day, mg/kg/day, (PO, mg/kg mg/kg/day mg/kg, SC, mg/kg IM mg/kg, mg/kg/d 3 14 PO mg/kg, PO mg/kg,

Toxic Otherwise 2 8 14 80 0.075 2 11 2.0 0.5 0.2 7.5 1.6 75 (LD 50 ) 55 (LD 50 )

mg/kg/d 3 12 PO mg/kg/day, mg/kg/day 3 18 PO mg/kg/day, mg/kg/d 3 53 PO PO mg/kg/day, SC 3 3d mg/kg, SC mg/kg, d mg/kg/day 3 14 PO mg/kg, IM SC mg/kg, topical mg/kg, d, mg/kg/d 3 14 d, mg/kg/d 3 14

Endectocides NOAEL 0.25 PO mo, 0.05 4 8 PO mo, 1 1.5 2 weeks, 1.6 2.5 0.6 2 0.25 mg/kg, 3 0.6 2.5 1 PO 5 PO

Lactone Dose SC SC IM, SC IM, Topical SC SC IM, SC IM, mg/kg IM q PO SC IM, topical topical topical topical topical

Macrocyclic Therapeutic (Route) mg/kg, 0.2 N/A N/A N/A N/A mg/kg 0.2 mg/kg 0.2 mg/kg, 0.5 mg/kg, 0.2 N/A N/A mg/kg 0.2 0.2 0.5 mg/kg 0.3 mg/kg 0.2 h 3 4d, 24 mg/kg 0.2 mg/kg, 0.5 mg/kg, 0.5 N/A mg/kg, 0.5 mg/kg, 1 N/A N/A mg/kg, 0.5

Various (CF-1, (CD-I) (breeding)

of Species (beagle) Mouse pregnant) Mouse (pregnant) (SD) (SD, pregnant) Camelids (beagle) (collie) Camelids Horses
Toxicity Cattle Dog Mouse Rabbit Rat Rat Rat Cattle Cattle Dogs Dogs Goats Lions Pigs Rats Sheep Cattle Dogs Goats Mice Rats Sheep

43.2

TABLE VetBooks.ir Agent Abamectin Doramectin Eprinomectin