Page 528 - Traité de chimie thérapeutique 6 Médicaments antitumoraux
P. 528

486               MEDICAMENTSINDUISANTOUSTABILISANTDES COUPURESDE L'ADN

             POLVERINI P.J., NOVAK R.F., Inhibition of angiogenesis by the antineoplastic agents
               mitoxantrone and bisantrene, Biochem. Biophys. Res. Commun., 1986, 140, 901-907.
             RYBAK M.E. et al., The effects of bisantrene on human platelets, lnvest. New Drugs,
               1986, 4, 119-125.

              MÉCANISME D'ACTION
              DOROSHOW J.H. et al., Comparative cardiac oxygen radical metabolism by anthracy-
               cline antibiotics, mitoxantrone, bisantrene, 4'-(9-acridinylamino)-methanesulfon-m-
               anisidide, and neocarzinostatin, Biochem. Pharmacol., 1983, 39, 2935-2939.
              BOWDEN G.T. et al., Comparative molecular pharmacology in leukemic L 1210 cells of
               the anthracene anticancer drugs mitoxantrone and bisantrene, CancerRes., 1985, 45,
                4915-4920.
              CHEN K.X. et al., lntercalative binding and antitumor activity of bisantrene and derivati-
                ves, /nt. J. Quantum Chem., Quantum Biot. Symp., 1987, 14, 15-25.
              ELLIOTT J.A. et al., Interaction of bisantrene anticancer agents with DNA : footprinting,
                structural requirements for DNA unwinding, kinetics and mechanism of binding and
                correlation of structural and kinetic parameters with anticancer activity, Anti-cancer
                Drug Des., 1989, 3, 271-282.
              MURDOCK K.C. et al., DNA Binding by antitumoranthracene derivatives, J. Med. Chem.,
                1990, 33, 1549-1553.
              PERRIN D. et al., Differential sensitivities of recombinant human topoisomerase Il a and
                B interacting agents, Biochem Pharmaco/., 1998, 56, 503-507.
              WUNZ T.P. et al., DNA binding by antitumor anthracene derivatives, J. Med. Chem.,
                1990, 33, 1549-1553.
              IYENGAR B.S. et al., 1,4-Disubstituted anthracene antitumor agents, J. Med. Chem.,
                1997, 40, 3734-3738.
              CAPRANICO G. et al., A protein-mediated mechanism for the DNA sequence-specific
                action of topoisomerase Il poisons, Trends Pharmacol. Sci., 1997, 18, 323-329.
               CAPRANICO G. et al., Mapping drug interactions at the covalent topoisomerase II-DNA
                complex by bisantrene/amsacrine congeners, J. Biol. Chem., 1998, 273, 12732-
                 12739.
               SISSI C. et al., DNA-binding preferences of bisantrene analogs : relevance to the
                 sequence specificity of drug-mediated topoisomerase Il poisoning, Mol. Pharmacol.,
                 1998, 54, 1036-1045.
               VENITT S. et al., Anthracene-9,10-diones as potential anticancer agents : bacterial
                 mutation studies of amido-substituted derivatives reveal an unexpected lack of muta-
                 genicity, J. Med. Chem., 1998, 41, 3748-3752.
               ZAGOTTO, G. et al., Synthesis, DNA-damaging and cytotoxic properties of novel topoi-
                 somerase 11-directed bisantrene analogs, Bioorg. Med. Chem. Lett., 1998, 8, 121-126.

               RÉSISTANCE
               ZHANG X. et al., P-glycoprotein mediates profound resistance to bisantrene, Oncol.
                 Res., 1994, 6, 291-301.
               ZHOU Y. et al., Domain exchangeability between the multidrug transporter (MDR1) and
                 phosphatidylcholine flippase (MDR2), Mol. Pharmacol., 1999, 56, 997-1004.
   523   524   525   526   527   528   529   530   531   532   533