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              25. ANTTPURINES

              IKEHARA M., TADA H.,  Studies of nucleosides. XXIV.  Purine cyclonucleosides.
                I. 8,2'-cyclonucleoside derived from 2-chloro-8-mercapto-9-[-D-xylofuranosylade-
                nine, J. Amer. Chem. Soc., 1965, 87, 606-610.
              CHRISTENSEN L.F., et al., Synthesis and biological activity of selected 2,6-disubstitu-
                ted-(2-deoxy-a- and - B-D-erythro-pentofuranosyl) purines, J. Med. Chem ., 1972, 15,
                735-739.
              KAZIMIERCZUK Z., et al., Synthesis of2'-deoxytubercidin, 2'-deoxyadenosine, and rela-
                ted 2'-deoxynucleosides via a novel direct stereospecific sodium sait glycosylation
                procedure, J. Amer. Chem. Soc., 1984, 106, 6379-6382.
              BEUTLER E., La cladribine (2-chlorodésoxyadénosine), Lancet, Ed. Fr., 1993, 29-33.
              BRYSON H.M., SORKIN E.M., Cladribine, a review of its pharmacodynamie and phar-
                macokinetic properties and therapeutic potential in haematological malignancies,
                Orugs, 1993, 46, 872-894.
              GOLLARD R., et al., The optimal management of hairy cell leukaemia, Drugs, 1995, 49,
                921-931.
              SONDEREGGER T. et al., Pharmacokinetics of 2-chloro-2'-deoxyadenosine administe-
                red subcutaneously or by continuous intravenous infusion, Cancer Chemother. Phar-
                macol., 2000, 46, 40-42.
              JANSSEN-CILAG, Dossier technique : LEUSTATINE-Cladribine, 1-78.
              FLUDARABINE
              MONTGOMERY J.A., HEWSON K., Nucleosides of 2-Fluoroadenine, J. Med. Chem.,
                1969, 12, 498-504.
              MONTGOMERY J.A., et al., An improved procedure for preparation of 9-P-D-arabinofu-
                ranosyl-2-fluoroadenine, J. Heterocyc/ic Chem., 1979, 16, 157-160.
              CHUN H.G., et al., Central nervous toxicity of fludarabine phosphate, CancerTreat. Rep.,
                1986, 70, 1225-1228.
              HERSH M.R., et al., Pharmacokinetic study of fludarablne phosphate (NSC 312887),
                Cancer Chemother. Pharmacol. 1986, 17, 277-280.
              PLUNKETT W. et al., Metabolism and action of fludarabine phosphate, Seminars in onco-
                logy, 1990, 17, n° 5, suppl. 8, 3-17.
              ROSS S.R. et a/., Fludarabine -a review of its pharmacological properties and therapeu-
                tic potential ln malignancy, Orugs, 1993, 45, 737-759.
              SCHERING, Dossier d'information : Phosphate de fludarabine.
              SCHERING, Dossier technique : FLUDARA.

              6-MERCAPTOPURINE
              ELION G.B., et al., Studies on condensed pyrimidine systems. IX. The synthesis of some
                6-substituted purines, J. Amer. Chem. Soc., 1952, 74, 411-414.
              ELION G.B., et al., Studies on condensed pyrimidine systems. XXI. The isolation and
                synthesls of 6-mercapto-2,8-purinediol (6-thiouric acid), J. Amer. Chem. Soc., 1959,
                81, 3042-3045.
              BEAMAN A.G., ROBINE R.K., Potential purine antagonists. XXVII. Synthesis and reac-
                tions of some purinesulfonyl fluorides, J. Amer. Chem. Soc., 1961, 83, 4038-4044.
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