Page 262 - fourth year book

DIABETES MELLITUS

resistance are considered genetics and weight gain. This first phase of
resistance stimulates an increase in insulin production by ß-cells. ß-cells

are unable to make enough insulin to meet the body’s perceived need.
As the insulin resistance continues hyperglycemia develops. ß-cell

failure due to ―exhaustion‖ or ―glucose toxicity‖ is believed to follow.
Autoimmune destruction of ß-cells does not occur in individuals with

Type 2.

Differences between different types of Diabetes :

Commonly recognized signs and symptoms :

Common signs and symptoms for both type 1 and type 2 diabetes include:

 Excessive excretion of urine (polyuria)

 Excessive thirst (polydipsia)
 Constant hunger (polyphagia).
 Weight loss.
 Vision changes
 Fatigue.

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