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C  CLINICAL RESEARCH




               Figure 5: A 62 year-old Caucasian man with concurrent optic nerve head drusen and ocular hypertension. The diffuse RNFL
               loss OD is more prominent than OS.

                  a)  In OD the tertiary vessels are clearly visible in the superior and inferior sectors since no RNFL overlies to
                     blur them. There is no obvious brighter pattern adjacent to relatively darker area temporally and nasally.

                  b)  OS shows some asymmetry between the area inferior and superior to the nerve. There is more diffuse loss
                     inferiorly than superiorly with a few visible striations noted superiorly. Tertiary vessels are clearer inferiorly
                     than superiorly.

























               Localized wedge defects are usually easier to detect. This type of defect is at least the width of a major retinal vessel
               (smaller slit defects are normal anatomic variations) and will widen as they extend in an arcuate pattern from the
               poles of the ONH. Most often, wedge defects will appear inferior- and/or superior-temporal. 183,184  These represent
               sites of active glaucomatous damage that are frequently accompanied by focal NRR notching, PPA, DH, and VF
               defects, and merit close scrutiny for widening or deepening. 185,186  Figure 6 shows an example of an inferior wedge
               defect that is clearly delineated by adjacent areas of prominent RNFL.



               Figure 6: A 67 year-old Persian woman with normal tension glaucoma. A well-defined dark wedge defect inferiorly is bor-
               dered by relatively brighter RNFL striations on either side. This is contrasted to the healthy RNFL striations and blurring of
               the tertiary vessels noted superiorly.




























      24             CANADIAN JOURNAL of OPTOMETRY    |    REVUE CANADIENNE D’OPTOMÉTRIE    VOL. 79  SUPPLEMENT 1, 2017
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