Page 45 - Ивермектинд адууны нематодын даслыг судалсан дүн
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Ивермектинд адууны нематодын даслыг судалсан дүн
gastrointestinal tract of horse and the dominant helminth species are Strongylus spp,
Parascaris sp, Oxyuris sp and Anoplocephala spp [29].
The feacal egg count reduction test (FECRT) is based on nematode biology,
where there is a direct correlation between the number of adult worms and released
egg or larvae output in the feces. The FECRT is the most effective method for the
detecting anthelmintic drug resistance in horses by comparing the numbers of
parasite eggs in the feces from an animal before and after treatment [39].
The main reasons for the development of anthelmintic resistance are frequent,
less controlled and long term usage of single anthelmintic drugs, and under-dosing
[15].
In Mongolia, the approach to improving race performance and horse let to a less
controlled and wider consumption of drugs, including AHs, and cross breeding in
racing stock for last 15-20 years. Macrocyclic lactones (MLs) have been used
commonly, with more frequent usage observed particularly in the racing horse
population, for the control of equine parasites over the last 20 years in Mongolia.
Therefore this study was conducted to check for the presence of resistance to
MLs (particularly ivermectin) in the targeted population.
OVERALL GOAL AND OBJECTIVES OF THE STUDY
The goal of the study was to check for ivermectin resistance in the dominant equine
helminth population. The following objectives were provided to meet this goal:
1. Use the fecal egg count reduction test (FECRT) to determine equine
gastrointestinal nematodes resistance to ivermectin.
2. Use the larval culture test to check equine gastrointestinal nematodes
resistant to ivermectin.
3. Provide recommendations on the use ivermectin to prevent equine
helminthiasis and to prevent resistance to AHs.
METHODS AND MATERIAL
Materials:
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