Page 44 - Хонь, ямааны цэцгийн вакцины сөөлжих идэвхийг сорьсон дүн

“Хонь, ямааны цэцгийн вакцины сөөлжих идэвхийг сорьсон дүн” 2015 он

Testing for cross protection of sheep and goat pox vaccine

Abstract

Body temperature of animals vaccinated against sheep and goat pox increased by

0
0
0.8 C to 1.2 C at days 1 to 4 after the vaccination and then it reached the normal
level. Challenge infection with “Stravropolskii” strain in sheep injected with cell-
culture live virus vaccine for prevention of sheep pox demonstrated that the vaccine
against sheep pox had 100% protection efficacy in sheep and 80% in goats. Keeping

of 3 sheep and 3 goats, which were not vaccinated against sheep pox, together with

vaccinated sheep and goats and challenge infection with “Stavropolskii” strain in
these animals resulted in infection of 3 sheep, while 3 goats remained not infected.

Challenge infection with “Kho” strain in goats and sheep injected with aluminium

hydroxide formol vaccine against goat pox virus led to infection of vaccinated 1 goat
and 2 sheep. After the challenge infection with “Kho” strain, while keeping 3 goats

and 3 sheep not vaccinated against goat pox virus, together with vaccinated sheep
and goats, all unvaccinated animals were infected. When virus of Pergo strain is

inoculated in cell sub-culture, the virus is started reproducing from hour 36 and all
culture cells were completely pathologic at hour 72. Results of our study revealed

cell-culture live virus vaccine against sheep pox is capable of protecting 100% of

sheep and 80% of goats. Therefore, it is seen that goats can be immunized with
sheep pox vaccine.

Keywords: sheep, goat, vaccine, cross protection

Background of the study: Mongolia is Central Asian country, bordering with
Russian federation in north and Peoples Republic of China in south. Therefore,

Mongolia is situated in the region with higher risk of transboundary diseases. One of
clear example of such is sheep and goat pox. Sheep populations account for 44.3%

of our country’s total livestock populations, while goats for 42.9%, which represent
majority of food producing animals in Mongolia.

It is seen to be necessary to investigate characteristics and efficacy of vaccine in

order to prevent sheep and goat pox.

Бүрэнмэндийн Баярцэцэг 44