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                                                                                       Chapter 3: Clinical 91


                  Table 3.1 Patterns of cough
                                                                                        Most likely
                  Onset        Timing      Precipitation  Symptoms       Sputum         diagnosis
                  Recent (days)                         Pyrexia, sinusitis,  White/clear  Common cold
                                                          sore throat
                  Recent (days)                         Pyrexia, malaise,  Rusty or purulent  Pneumonia, acute
                                                          dyspnoea        (yellow/green)  bronchitis
                  Chronic      Worst                    Smoker           White/clear    Chronic bronchitis
                                mornings
                  Chronic                                                Large volume   Bronchiectasis
                                                                          purulent
                  Intermittent,  Night     Exercise, pets,  Wheeze       Yellow/white   Asthma
                    recurrent   time/early  pollen,                       (eosinophils)
                                morning     smoke, etc.
                  Recent                                Smoker, weight   Haemoptysis    Carcinoma until proved
                    (weeks)                               loss, occasionally              otherwise (often
                                                          dull chest pain                 associated pneumonia)


                  specific size of airway – usually one bronchus) or poly-  creased airway pressure opens the valve, so expiratory
                  phonic (widespread airway limitation). Asthma is one  wheeze may be minor.
                  of the major causes of polyphonic wheeze, but not all     Acute stridor: Laryngeal trauma or smoke/toxic gas
                  asthmaattacksareaccompaniedbywheeze.Othercauses  inhalation, acute epiglottitis (drooling, unwell), ana-
                  include chronic obstructive airways disease and acute  phylaxis, inhaled foreign body.
                  bronchitis.                                      Gradual onset: Obstruction by tumours of the upper
                    Stridor is due to upper airway obstruction. It occurs  airway (larynx, pharynx or trachea), extrinsic com-
                  because in inspiration, a valve-like effect worsens ob-  pression (lymph nodes, retrosternal thyroid), bilateral
                  struction in the major airways. On expiration, the in-  vocal cord palsy.


                  Table 3.2 Causes of dyspnoea
                  Timing         Cause                        Accompanying features
                  Acute          Inhaled foreign body         There is usually a history or suspicion
                                 Pneumothorax                 Pleuritic (sharp, worse on inspiration) chest pain, hyper resonant,
                                                               no air entry
                                 Pulmonary embolism           Pleuritic chest pain, haemoptysis, risk factors
                  Hours          Asthma                       Intermittent, previous history of atopy/asthma, precipitating
                                                               factors, e.g. cold, exercise, allergy
                                 Pneumonia                    Pleuritic chest pain, pyrexia, purulent sputum, lung dull to
                                                               percussion with bronchial breathing.
                                 Pulmonary oedema             Cardiac history, intermittent (exertional, orthopnoea, paroxysmal
                                                               nocturnal dyspnoea) or acute – basal crackles, frothy sputum,
                                                               cardiac chest pain
                                 Extrinsic allergic alveolitis  Recurrent, occupational exposure
                  Days/weeks     Pleural effusions            Dull to percussion, reduced breath sounds
                                 Carcinoma of the bronchus/   Obstruction causes collapse and consolidation of lung.
                                   trachea                     Haemoptysis, clubbing, weight loss.
                  Months/years   Chronic bronchitis/emphysema  Smoking history, cough & sputum
                                 Idiopathic pulmonary fibrosis  Clubbing and cyanosis, fine crackles
                                 Occupational fibrotic lung disease  Occupational history
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