Page 1059 - Small Animal Internal Medicine, 6th Edition
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CHAPTER 57   Neonatology and Pediatrics   1031





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             A                                               B

                        FIG 57.33
                        (A) Intracranial ultrasound using a trans (open) fontanelle approach. (B) Resultant
                        ultrasound image showing an increased amount of cerebrospinal fluid present in the
                        ventricles.




            neonatal resuscitation earlier) (Grundy et al., 2009). The   Treatment includes gentle manual separation of the lids and
            normal neurologic examination of the pediatric canine has   topical triple antibiotic ointment (erythromycin in kittens).
            been reported (Lavely, 2006). Weak or ataxic ambulation   Microphthalmos, enophthalmos, strabismus, distichiasis,
            can indicate a neurologic or musculoskeletal abnormal-  and  entropion  become  apparent  after  the  eyelids  separate.
            ity. Morphologic neurologic abnormalities occur most fre-  Temporary eyelid tacking (puppy  <4 months of age) with
            quently. Hydrocephalus has an increased frequency in toy   2 to 4 vertical mattress sutures can preclude or postpone
            and brachycephalic breeds, and can occur in cats. A domed   surgical correction of entropion. Congenital cataracts can
            calvarium, open fontanelle, and prominent suture lines are   be genetic, secondary to in utero conditions (drugs, toxins,
            often present. Aqueduct atresia, birth trauma, or meningo-  nutritional), and amino acid deficiencies in artificial milk
            encephalitis can cause the development of hydrocephalus.   products. Epiphora can be secondary to increased lacrima-
            Clinical signs vary from inapparent to progressively debili-  tion from ocular irritation or imperforate or stenotic naso-
            tating. Ultrasound, possible through the open fontanelle   lacrimal puncta. Medial canthal trichiasis causes wicking of
            typical of brachycephalics, can confirm the presence of exces-  tears onto the facial folds; this is also recognized with shallow
            sive cerebrospinal fluid within the ventricles (Fig. 57.33, A,   lacrimal space seen in brachycephalic breeds. Keratocon-
            57.33, B). Cranial and spinal dysraphism occur secondary to   junctivitis sicca can be congenital in some breeds (York-
            embryologic defects in neural tube closure. The presence of   shire Terrier) or secondary to canine distemper virus and
            resultant neurologic defects generally warrants euthanasia.   herpesvirus in kittens. Prolapse of the third eyelid gland
            Vertebral anomalies include hemivertebrae, fused vertebrae,   occurs in brachycephalic dogs and the Burmese cat; preser-
            and butterfly vertebrae, and are usually subclinical unless   vation of tear production is accomplished by anchoring the
            spinal cord compression occurs. Cerebellar hypoplasia and   gland in place rather than excising it. Congenital disorders
            abiotrophy cause truncal ataxia, hypermetria, and intention   of metabolism can result in corneal opacities.
            tremor at the onset of ambulation. Abiotrophy is progres-
            sively debilitating and may occur with lissencephaly. Dysmy-  Dermatologic Disorders
            elination and hypomyelination of the central nervous system   Juvenile cellulitis is a progressive granulomatous pustular
            cause tremors with onset by 1 to 2 weeks of age.     disorder of puppies. Immunosuppression is indicated for
                                                                 resolution and prevention of severe cicatricial lesions. It is
            Ophthalmologic Disorders                             most common in dogs younger than 4 months of age but is
            Ocular anomalies account for 15% of all congenital defects   occasionally reported in dogs up to 4 years old. The eyelids,
            in puppies and 9% in kittens. Eyelid agenesis occurs most   pinnae, lips, chin, muzzle, paws, abdomen, thorax, vulva,
            commonly in kittens and is apparent at birth. Neonatal   prepuce, and anus can be affected with lesions that fistulate,
            ophthalmia becomes apparent before the eyelids separate   drain, and crust (Fig. 57.34, A, 57.34, B). Lymphadenomeg-
            at 10 to 14 days of life (see Fig. 57.19). Bacterial infection is   aly, most commonly mandibular and superficial cervical, can
            most likely in puppies, viral (Herpes, chlamydia) in kittens.   be distant from the affected skin sites and is often painful
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