Page 1063 - Small Animal Internal Medicine, 6th Edition
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CHAPTER 57   Neonatology and Pediatrics   1035




  VetBooks.ir  Drugs Used in Reproductive Disorders—cont’d          CANINE DOSE             FELINE DOSE

                                                 TRADE NAME
                                DRUG
             USE
                                Aglepristone     Alizine, Virbac    10 mg/kg SC, twice, 24 hr  10 or 15 mg/kg SC,
                                                                     apart                    twice, 24 h apart
                                Cabergoline      Galastop,          5 µg/kg PO q24h, 3-5
                                                   Boehringer        days, begin ≥ day 49
                                                   Ingelheim;
                                                   Dostinex, Pfizer
                                                 Lutalyse, Zoetis   0.1-0.2 mg/kg SC q8-12h,   0.1-0.2 mg/kg SC
                                PGF 2α
                                                                     begin ≥ day 35, until    q12h, begin day 45,
                                                                     abortion complete        until abortion
                                                                    Plus misoprostol 1-3 µg/kg,   complete
                                                                     intravaginally, q24h until
                                                                     abortion complete
                                                 Dexamethasone      0.2 mg/kg PO, twice daily
                                                                     to effect
             Agalactia          Oxytocin 10 U/mL  Various           0.25-1 U/dog SC, 30 min   0.25-1 U/queen SC,
                                                                     before nursing for milk   30 min before nursing
                                                                     letdown                  for milk letdown
                                                                    and                     and
                                Metoclopramide   Reglan,            0.1-0.2 mg/kg, PO or SC,   0.1-0.2 mg/kg, PO or
                                                   Wyeth-Ayerst      q12h for milk production  SC, q12h for milk
                                                                                              production
             Benign prostatic   Finasteride      Proscar and        0.1-0.5 mg/kg
               hyperplasia                         Propecia, Merck  or
                                                                    5 mg/dog PO q24h
             Dystocia*          Calcium gluconate   Various         10% solution 1 mL/4.5 kg   10% solution
                                 SC or IM                            SC q4-6h; give in        1 mL/4.5 kg SC
                                                                     multiple sites if > 6 mL.   q4-6h; give before
                                                                     Give before oxytocin.    oxytocin
                                Oxytocin SC or IM  Various          0.25-2 U/bitch, SC or IM,   0.25-2 U/queen, SC or
                                                                     q30-60 min to maintain   IM, q30-60 min to
                                                                     normal labor pattern     maintain normal labor
                                                                                              pattern
             Estrus induction   Cabergoline      Galastop,          5 µg/kg PO q24h, until 2
               during anestrus                     Boehringer        days after onset of
                                                   Ingelheim;        cytologic proestrus
                                                   Dostinex, Pfizer
                                Deslorelin       Ovuplant, Fort     1.05 or 2.1 mg, SC
                                                   Dodge             implant in vestibular
                                                                     mucosa in ventral
                                                                     commissure of vulva;
                                                                     remove when in proestrus
                                                                                            eCG 100 IU IM
                                                                                            Followed in 80-84 h
                                                                                              with hCG 75-100 IU
                                                                                              IM
             Estrus suppression  Deslorelin      Ovuplant, Fort     6-12 mg, SC implant †   6 mg, SC implant
                                                   Dodge
             False pregnancy    Cabergoline      Galastop,          5 µg/kg PO q24h to effect
                                                   Boehringer        (usually 3-5 days)
                                                   Ingelheim;
                                                   Dostinex, Pfizer
                                                                                                          Continued
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