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CHAPTER 2   Diagnostic Tests for the Cardiovascular System   35



                                                                        TABLE 2.3
  VetBooks.ir                                                    Normal Cardiac Waveforms

                                                                               EVENT
                                                                  WAVEFORM
                                                                  P            Depolarization (activation) of atrial
                                                                                 muscle; normally is positive in leads II
                                                                                 and aV F
                                                                  PR interval  Time from onset of atrial muscle
                                                                                 activation, through conduction over
                                                                                 the AV node, bundle of His, and
                                                                                 Purkinje fibers; also called PQ interval
                                                                  QRS complex  Depolarization of ventricular muscle; by
                                                                                 definition, Q is the first negative
                                                                                 deflection (if present), R the first
                                                                                 positive deflection, and S is the
                                                                                 negative deflection after the R wave
                                                                  J point      End of the QRS complex (and ventricular
                                                                                 muscle activation); junction of QRS
                                                                                 and ST segment
                                                                  ST segment   Represents the period between
                                                                                 ventricular depolarization and
                                                                                 repolarization (correlates with phase 2
                                                                                 of the action potential)
                                                                  T wave       Ventricular muscle repolarization
            FIG 2.24
            Normal canine P-QRS-T complex in lead II. Paper speed is   QT interval  Total time of ventricular depolarization
            50 mm/sec (0.02 sec per each small box); calibration is              and repolarization
            standard (1 cm = 1 mV, 0.1 mV per each small box). Time
            intervals (seconds) are measured from left to right; waveform   AV, Atrioventricular.
            amplitudes (millivolts) are measured as positive (upward) or
            negative (downward) motion from baseline.



            complex, as a representation of ventricular muscle electri-  electrical potential differences between two electrodes on the
            cal activation, does not necessarily have individual Q, R,   body  surface;  the  lead  axis  is  oriented  between  these  two
            and S wave components (or variations thereof). The con-  points. Unipolar leads have a recording (positive) electrode
            figuration of the QRS complex depends on the lead being   on the body surface. The negative pole of unipolar leads is
            recorded, as well as the animal’s intraventricular conduction    formed by “Wilson’s central terminal” (V), which is an
            characteristics.                                     average of all other electrodes and is analogous to zero.
                                                                   The standard limb lead system records cardiac electrical
            LEAD SYSTEMS                                         activity in the frontal plane (as depicted by a DV/VD radio-
            Various leads are used to evaluate the cardiac activation   graph). In this plane, left-to-right and cranial-to-caudal cur-
            process. The orientation of a lead with respect to the heart is   rents are recorded. Fig. 2.25 depicts the six standard frontal
            called the lead axis. Each lead has direction and polarity. If   leads (hexaxial lead system) overlying the cardiac ventricles.
            the myocardial depolarization or repolarization wave travels   Unipolar limb leads are “augmented” (aVF, etc.) because
            parallel to the lead axis, a relatively large deflection will be   their voltage is so low. Unipolar chest (precordial) leads
            recorded in that lead. As the angle between the lead axis and   “view” the heart from the transverse plane (Fig. 2.26). Box
            the orientation of the activation wave increases toward 90   2.2 lists common ECG lead systems.
            degrees, the ECG deflection for that lead becomes smaller;
            it becomes isoelectric when the activation wave is perpen-  APPROACH TO ECG INTERPRETATION
            dicular to the lead axis. Each lead has a positive and a nega-  Routine ECG recording usually is done with the animal
            tive pole or direction. A positive deflection will be recorded   placed in right lateral recumbency on a nonconducting
            in a lead if the cardiac activation wave travels toward the   surface. The proximal limbs are parallel to each other and
            positive pole (electrode) of that lead. If the wave of depolar-  perpendicular to the torso. Other body positions may change
            ization travels away from the positive pole, a negative deflec-  the various waveform amplitudes and affect the calculated
            tion will be recorded in that ECG lead. Both bipolar and   mean electrical axis (MEA). However, if only heart rate and
            unipolar ECG leads are used clinically. A bipolar lead records   rhythm  are  desired,  any  recording  position  can  be  used.
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