Page 445 - The Veterinary Laboratory and Field Manual 3rd Edition

Plate 49 See also Figure A2.10 Liver,
sheep. Chronic fascioliasis (Fasciola
hepatica). F. hepatica is a liver fluke
commonly associated with acute and
chronic liver disease in small ruminants.
Acute disease manifests as sudden
death as a result of overwhelming
hepatocellular necrosis caused by
large number of larval flukes migrating
through the parenchyma. Chronic
fascioliasis occurs are a result of chronic
cholangiohepatitis as a result of the
presence of adult flukes within bile
ducts. In this image, a tangle of adult
flukes can be seen within the lumen
of a large bile duct at the hilus. The left
lobe is atrophic, fibrotic bile ducts are
visible from the cut section and the right
lobe is hypertrophied. This appearance
is characteristic but it is unclear why
the left lobe is preferentially affected.
In addition, the hilar lymph nodes are
enlarged as a result of chronic antigenic
stimulation. . Photo: Mr R. Irvine,
University of Glasgow, UK.

Plate 50 See also Figure A2.11 Kidney,
bovine. Autolysis. Autolysis occurs more
rapidly in organs containing higher levels
of proteolytic enzymes such as the liver
and kidney or that contain large amounts
of bacteria such as the GI tract. In this
case the kidney is pallid and has lost
structure appearing diffusely softened.
Note also fine emphysematous gas
bubbles in the tissue. Photo: Mr R.
Irvine, University of Glasgow, UK.

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