Page 650 - Adams and Stashak's Lameness in Horses, 7th Edition
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616   Chapter 5




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                             A                                     B

                   Figure 5.19.  Radiographs demonstrating mild signs of osteoarthritis, including enthesophyte (A; arrow) and osteophyte
                                                   (A, B; arrowheads) formation.


              Surgery can be performed to remove osteochondral   that this can lead to worsening of pain. A mild lateral
            fragments or for augmentative therapies such as microf-  extension or a full shoe itself may help to alleviate some
            racture and resurfacing; however, the disease process   of this pain by slowing the dorsolateral break‐over that
            will likely continue to progress postoperatively, and in   occurs. In severe cases of OA, partial or pancarpal
            most cases the goal of surgery is to help relieve pain and   arthrodesis is often advocated to reduce the amount of
            the severity of the disease.                       chronic pain in the limb and prevent laminitis in the
              Intra‐articular medication is meant to treat the synovi-  opposing limb.
            tis component that often leads to pain, but its efficacy for
            treating subchondral bone damage is questionable. Intra‐
            articular corticosteroid and hyaluronic acid combinations   CARPOMETACARPAL OSTEOARTHRITIS
            may work for a short period of time but often stop work-
            ing. Intra‐articular hyaluronic acid and polysulfated   OA of the carpometacarpal joint is a separate syn-
              glycosaminoglycan combinations or IRAP may be con-  drome that predominantly involves mainly Quarter
            sidered. In some cases, there is subjective evidence to   horses and Arabian horses. 73,96  The osteoarthritic changes
            show that intra‐articular administration of stem cells may   manifest mostly at the articulation between the second
            be helpful in managing horses with carpal OA. Although   carpal and second metacarpal bones and radiographi-
            it is thought that only triamcinolone acetonide or beta-  cally show osteoproliferative changes and joint space
            methasone should be used in high‐motion joints such as   narrowing medially (Figure 5.20). Lameness is insidious
            the carpus, methylprednisolone acetate may be the only   in onset, but can progress rapidly. The etiology of this
            thing that is effective in some cases of severe OA. Although this   problem is unknown, but it has been suggested that an
            has been shown experimentally to result in progressive   anatomic abnormality may exist between the second and
            articular cartilage damage, in these cases management of   third carpal bones.  Medical management of these cases
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            pain is often considered the priority. It is sometimes diffi-  can be frustrating over time because they typically
            cult to determine the origin of the greatest site of pain in   become less responsive to treatment.  Similar to OA at
                                                                                               96
            horses with carpal OA. In cases with severe osteophyte   other sites, medical management is worth attempting
            and enthesophyte formation and subsequent reduced   until there is concern that the lameness could contribute
            range of motion, the author has occasionally used corti-  to opposing limb laminitis. At this point, a partial carpal
            costeroids administered via regional limb perfusion of the   arthrodesis could be performed. Partial carpal arthrode-
            carpus to help alleviate pain. Further studies are needed   sis can be performed in one of two ways. Barber et al.
            to evaluate the efficacy of this treatment, but in some   evaluated a drilling technique for arthrodesis in 12 horses
            cases it seemed to be effective.                   and found that it was considered successful in most
              Medial collapse of the carpal joints is not uncommon   cases.  However when evaluated experimentally, the
                                                                    8
            in severe cases of OA, and often dorsolateral break‐over   same technique failed to produce consistent ankylosis in
            of the hoof in that limb is noticeable. This progressively   normal joints.  Consequently, some surgeons have advo-
                                                                           97
            worsens between trimmings; it is a subjective opinion   cated plate fixation to fuse the joint.
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