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150  Section 3  Cardiovascular Disease


  VetBooks.ir                                  Left apical (or caudal)
                                                 4-chamber view












              Slight rotation
                to the left                                 Slight rotation
                                                              to the left
                       Left apical (or caudal)
                          5-chamber view






















            Figure 16.18  Two‐dimensional left apical (or caudal) four‐ and five‐chamber views. The top image on the left shows spatial orientation
            of the ultrasound beam, with the transducer placed on the left side of the thorax, to obtain the left apical four‐chamber view. As
            shown in the top image on the right, the ultrasound plane goes first through the apex, then the right (RV) and left (LV) ventricles, and
            lastly the left and right atrial cavities (LA and RA, respectively). Therefore, the real‐time two‐dimensional left apical four‐chamber view
            shows the apex and the two ventricles at the top of the sector image, and the two atrial cavities below, with the mitral valve opened
            during diastole and closed from end‐diastole to end‐systole (middle and right bottom images, respectively). The left apical four‐
            chamber view can be used to measure maximum end‐systolic and end‐diastolic LV length as well as LV volumes. An example of
            calculation of end‐diastolic LV volume using the Simpson’s derived method of discs is provided on the bottom right image. The
            endocardial border has been traced and closed around the mitral annulus, thus delimiting the end‐diastolic LV area. The end‐diastolic
            LV volume, considered as the summation of parallel cylinders, whose diameters are derived from endocardial border tracing, is then
            automatically calculated using a specific software (62 mL). Another method, also called the length‐area method, relies on the following
                                     2
            simple formula: LV volume = 0.85A /L, where A is the LV area, and L is the LV length measured on the same view. From the left apical
            four‐chamber view, a slight rotation of the transducer to the left allows visualization of the left ventricular outflow tract and a long‐axis
            image of the aorta (Ao), thus defining the left apical five‐chamber view (bottom image on the left). See also Figures 16.22 and 16.27 as
            examples for use of the latter view. Source: Tessier-Vetzel D and Chetboul. In Chetboul et al. 2005.



             Box 16.1  Measurement of ventricular volumes
             Echocardiography can be used to measure ventricular     following formula: 100*(EDV‐ESV)/EDV, with EDV and
             volume using a variety of methods, including the   ESV corresponding to the end‐diastolic and end‐systolic
             Simpson’s derived method of discs or length‐area   left ventricular volumes. The end‐systolic volume index,
             method (see explanation in the legend of Figure 16.18).   defined as the end‐systolic left ventricular volume
             The left ventricular ejection fraction (expressed as a per-  divided by the body surface area, may be used as an
             centage) can then be calculated according to the   index of systolic myocardial function.
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