Page 107 - Avian Virology: Current Research and Future Trends

100 | Paldurai and Samal

Figure 8 100 *APMV-21 strain Cheonsu/1510 (MF594598.1)
100 APMV-9 strain New York (NC 025390)
APMV-16 strain UPO216 (KY511044)
100 100 APMV-1 strain LaSota (JF950510)
APMV-13 strain Shimane/67 (NC 030231)
100
100 APMV-12 strain Italy/3920-1 (NC 025363)
APMV-19 strain APV-C (KY452444)
100 APMV-18 strain APV-B (KY452443)
100 APMV-17 strain APV-A (KY452442)
APMV-4 strain Hong Kong (FJ177514)
100 APMV-3 strain Wisconsin (NC 025373)
100 APMV-3 strain Netherlands (EU403085)
100 APMV-6 strain Italy/4524-2 (GQ406232)
100 APMV-6 strain Hong Kong (EU622637)
100 APMV-5 strain Kunitachi (GU206351)
APMV-14 strain 11OG0352 (KX258200)
86 APMV-11 strain France/100212 (NC 025407)
100
APMV-7 strain Tennessee (NC 025347)
APMV-15 strain RS-1177 (NC 034968)
81
26 APMV-8 strain Delaware (FJ215863)
100 APMV-20 strain Kazakhstan/5976 (MF033136.2)
69 APMV-10 strain Falkland Islands/324 (HM147142.3)
61 APMV-2 strain Bangor (HM159995)
100 APMV-2 strain Yucaipa (EU338414)

0.10
Figure 3.8 Phylogenetic analysis of APMVs based on genome sequences. The evolutionary history was inferred based on the complete
genome sequences of APMVs by using the Maximum Likelihood method based on the Kimura 2-parameter model (Kimura, 1980) in MEGA7
(Kumar et al., 2016). The GenBank database accession number for each genome sequence is given in the parenthesis. (unless otherwise
mentioned, the genome sequences of the prototype APMV strains cited in this figure are the sources for all genome, gene and protein
*
sequence analyses performed in this Chapter). Putative APMV serotype awaiting official recognition from the ICTV.

(A)

(B)

Figure 3.9 Schematic representation of fusion protein (A) and haemagglutinin-neuraminidase protein (B) of avian paramyxovirus serotype
2 strain Yucaipa. A) White boxes indicate different domains of the APMV-2 fusion (F) protein: SP-signal peptide, FP-fusion peptide,
HRA-heptad repeat A, HRB-heptad repeat B. The subunits F1 and F2 are linked by disulfide bond. C-C, hyphenated Arabic numerals,
indicate locations of potential disulfide bonded cysteines in the fusion protein. B) White boxes indicate different domains of the APMV-2
haemagglutinin-neuraminidase (HN) protein: Stalk and globular head constitute the HN ectodomain. TM, CT, lines with bidirectional
arrow heads along with the hyphenated Arabic numerals and the filled-spade along with the Arabic numeral in panels A and B indicate
transmembrane domain, cytoplasmic tail domain, the amino acid length of each domain and the location of glycosylation sites, respectively.
The F and HN protein features of other APMV serotypes are summarized in Tables 3.5 and 3.6, respectively.