Page 93 - Children Bookt.pdf
P. 93
Fixed-dose AZT60mg + Adults and See comments under
combination 3TC30mg + adolescents AZT180-240mg/m 2 twice individual drugs components
of AZT [* a day
plus 3TC 3TC4mg/kg twice a day N0 food restriction
[* AZT300mg + [* j}!!&
3TC3150mg +
[*
protease inhibitors
Lopinavir/ Oral solution: 6 moths of *!
Preferably oral solution
2
ritonavir, 80mg/ml Lopinavir age or older 230-350mg mg/m twice and capsules should be
*
plus daily refrigerated; however, can
20 mg/ml ritonavir weight-based dosing: store at room temperature up
7-15kg: to 25`C (77`F) for 2 months;
- Heat stable 12mg/kg lopinavir - at temperature >25`C
paediatric tablets 3 mg/kg ritonavir (77`F),
dose twice daily drug degrades more rapidly
100mg Lopinavir
plus 15-40 kg: Liquid formulation has low
25 mg ritonavir 10 mg/kg lopinavir volume but bitter taste
2.5 mg/kg ritonavir Capsules large
Adult tablets twice daily Capsules should not be
200mg Lopinavir crushed or opened, but must
plus Maximum dose: be swallowed whole
50 mg ritonavir > 40 kg: Should be taken with food
400 mg lopinavir Drug interactions
100 mg ritonavir
twice daily
85
