Page 90 - Children Bookt.pdf
P. 90
Pharma-
Age (weight), dose and dose
Name of drug Formulations cokinetic data Other comments
frequency
available
Can give with food . Tablet can
be crushed and contents mixed
with small amount water or food
andimmediately ingested
< 16 years or < 37.5 kg:
8 mg/kg/dose twice daily MUST WARN PARENTS ABOUT
Oral solution: 20 mg/ml Over age 3
Abacavir (ABC) Maximum dose: =[$$*$
Tablet: 60 mg,300mg months
&!
'" ${[
300 mg/dose twice daily
ABC should be stopped
permanently if
hypersensitivity reaction occurs
Paediatric Tablets
ABC 60 mg +
Fixed-dose
3TC 30 mg tablets
combination Adolescents and ABC 8mg/kg twice daily
Adult tablets See comments under individual
of Abacavir adults
ABC 600 mg + drug components
(ABC) plus 3TC 4mg/kg twice daily
3TC 300 mg No food restriction
Lamivudine
No liquid available See comments under individual
Adult Tablet: drugs components
Fixed-dose
^*' ^* }!&
combination
3TC 150mg + Adolescents and Must warn patient about
^*
ABC 300 mg adults 3TC 4mg/kg twice daily hypersensitive reaction
plus 3TC plus
Paediatric Tablet:
ABC
^* ABC 8mg/kg twice daily ABC should be stopped
3TC 30 mg + permanently if hypersensitivity
ABC60 mg reaction occurs
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