Page 89 - Children Bookt.pdf
P. 89
- Large volume of solution
- Keep solution refrigerated;
stable for 30 days; must shake
< 30 kg: 1 mg/kg/dose twice well. Needs to be stored in glass
Oral solution: 1 mg/ml
daily bottles.
Stavudine (d4T) All ages - Capsules can be opened up and
Capsules: 15 mg, 20
>25kg kg: 30 mg/dose twice mixed with small amount of food
mg, 30 mg,
daily or water (stable in solution for 24
hours if kept refrigerated)
^
}^*
(antagonistic antiretroviral effect)
No liquid available
$!&!?
?
Fixed Tablet:
d4T 1mg/kg twice daily
combination of d4T6mg+3TC30 mg Adolescents and
See comments under individual
d4t plus 3TC d4T12mg+3TC60mg adults
3TC-4mg/kg t twice daily drug components
d4T30mg+3TC150 mg
Keeps suspension refrigerated;
stable for 30 days; must shake
well
Oral suspension
$
!
!&
paediatric powder/
< 3 mon: given as an enteric formulation
water: 10 mg/ml.
2
50mg/m /dose twice daily (or) combined with buffering
Didanosine $
!
&
agents (or) antacids
$ needs to be made up
3 mon to < 13 yrs:
with additional antacid.
2
90-120 mg/m /dose twice daily $
All ages !
!
$ !&
!:
Chewable(buffered)
Maximum dose: to be administered on an empty
tablets: 25 mg; 50 mg;
'&
stomach
100 mg;200mg
200 mg/dose twice daily or $!?
}!
!
Enteric-coated
400 mg once daily least 2 of appropriate strength
beadlets in capsules:
tablets should be dissolved for
125mg; 200 mg;250
adequate buffering
mg; 400 mg
- Enteric-coated beadlets in
capsules can be opened and
sprinkled on small amount of food
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