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Chapter 8  White cells: Granulocytes and monocytes  /  109



                       The white blood cells (leucocytes) may be divided   comprise the phagocytes. Their normal develop-

                      into two broad groups: the phagocytes and the   ment and function, and benign disorders are dealt
                      immunocytes. Granulocytes, which include three   with in this chapter. Only mature phagocytic cells
                      types of cell  –  neutrophils (polymorphs), eosi-  and lymphocytes are found in normal peripheral

                      nophils and basophils  –  together with monocytes   blood (Table  8.1 ; Fig.  8.1 ). The lymphocytes, their



                            Table 8.1   White cells: normal blood counts.

                              Adults             Blood count            Children             Blood count
                                                        9


                              Total leucocytes           4.00 – 11.0    ×   10  /L *               Total leucocytes
                                                      9
                                                                                                     9



                            Neutrophils          2.5 – 7.5    ×   10  /L *             Neonates         10.0 – 25.0    ×   10  /L
                                                                                                     9

                                                       9
                            Eosinophils          0.04 – 0.4    ×   10  /L         1 year        6.0 – 18.0    ×   10  /L

                                                      9
                                                                                                     9
                            Monocytes            0.2 – 0.8    ×   10  /L         4 – 7 years        6.0 – 15.0    ×   10  /L


                                                                                                     9
                            Basophils            0.01 – 0.1    ×   10  /L         8 – 12 years        4.5 – 13.5    ×   10  /L
                                                       9


                                                      9
                            Lymphocytes          1.5 – 3.5    ×   10  /L

                                *   Normal black and Middle Eastern subjects may have lower counts. In normal pregnancy the upper limits are: total


                        leucocytes 14.5    ×   10  /L, neutrophils 11    ×   10  /L.
                                     9
                                                   9

                      (a)                         (b)                          (c)













                      (d)                         (e)

                                Figure 8.1   White blood cells (leucocytes):  (a)  neutrophil (polymorph);  (b)  eosinophil;  (c)  basophil;  (d)  mono-


                      cyte;  (e)  lymphocyte.
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