Page 86 - Physiology and Pathophysiology MNU 2024-2025 نظرى

Clinical pharmacy 2024/2025 Level 2 Pharm D Physiology and Pathophysiology (MD303)

FSH (LH)

In a. Stimulates the development a. Cause the rupture of the follicle 
females of the ovarian follicles. release of the ovum  conversion of the
b. Induces the secretion of ovarian follicle into a corpus luteum

estrogen from the follicle (yellow body).
b. Induces secretion of estrogen &
progesterone from the corpus luteum.

In Acts on the Sertoli cells of the Acts on the Leydig cells of the testes to
males testes, which are involved with stimulate secretion of testosterone.
production of sperm.

NB

The release of FSH and LH is regulated by the hypothalamic releasing hormone,

gonadotropin-releasing hormone (GnRH).

5- Thyroid-stimulating hormone (TSH, thyrotropin)

a. Regulates the growth & metabolism of the thyroid gland.

b. Stimulates synthesis & release of the thyroid hormones  T3 & T4.

The release of TSH from the thyrotrope cells of the adenohypophysis is induced by
thyrotropin-releasing hormone (TRH).

IV. Thyroid gland

| P a g e 62