Page 132 - Applied Pharmacognosy
P. 132
Mobile Phase Selection
❑ If the sample is a hydrocarbon or if there are large hydrocarbon
groups around the hydrogen bonding sites that act as steric
hindrances, elution tends to occur sooner.
SiOH HO
Strong
SiOH
Very weak Weak
OH
Steric hindrance Normal Phase Separat1i3o1 n
