Page 267 - Pharmaceutics IV (02-06-01305)

3/30/24

Advantages of DPI

The spraying mechanism consists in transferring the powder in the container into
an aerosol form containing suspended solid particles
Most often the drug is sprayed as a result of the patient inhaling, which minimizes
the problem of poor coordination of the released dose with the patient’s inhaling,
which is faced by MDI
spraying devices - unlike pressurized inhalers, they do not require propellants
Aerosol deposition is much greater and there is no irritation.in the upper
respiratory tract in relation to MDI
High repeatability of the dose, small and comfortable sizes and low price

Well tolerated and willingly chosen by patients

Prof Alyaa Ramadan, ceutics, AU

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Powder characteristics

Good flow Lack of adhesion to
the material of
package

Low and uniform
particle size for
deposition in the An adequate low
appropriate region of drug dose.

the lung Prof Alyaa Ramadan, ceutics, AU

42

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