Page 114 - Pharmacognosy 02-06203

Active constituents:
1- Terpenoids; triterpene glycosides:
Actein, an active component from the herb black cohosh, has been
shown to inhibit the proliferation of human breast cancer cells.
2- Alkaloids: Quinolizidine–type.
3- Tannins: Tannic and gallic acid.

Action approved by commission E:
1- Estrogen-like action
2- Lutenizing hormone suppression 3-
Binding to estrogen receptors.

Uses:
• An effective remedy for problems related to the female reproductive
system.
• Black cohosh has commonly been used to treat symptoms of
menopause (neurovegetative aliments such as hot flashes),
premenstrual syndrome (PMS), dysmenorrhea, painful
menstruation, acne, weakened bones (osteoporosis), and for starting
labor in pregnant women.
• Black cohosh root also seems to have some effects similar to the
female hormone, estrogen.

Unproven uses:
The herb is also available commercially in combination with St.
John's Wort for depressive moods associated with premenstrual and
menopausal symptoms.

Contraindications:
The use of Black Cohosh is contraindicated during pregnancy due to
an increased risk of spontaneous abortion.

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