Page 111 - Pharmacognosy 02-06203
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4- Gelsemium

            1-Hydrastis (Golden seal rhizome, yellow root)

   Dried roots and rhizomes of Hydrastis canadensis, family Runnculaceae.

   Constituents:
     1- Isoquinoline yellow alkaloids (hydrastine, canadine and berberine).
     2- Resins, volatile oils and starch.

   Uses:
     1- Used for centuries for the treatment of mouth sores, whooping cough,
         pneumonia, digestive disorder and postpartum haemorrhage.
     2- The alkaloids can reduce gastric inflammation, relieve congestion,
         and destroy many types of bacterial and viral infections
           - Echinacea combined with goldenseal is one of the top-selling
               botanical dietary supplements in the US as immuno-stimulants.
           - Berberine, inhibits the proliferation of oesophageal cancer cell
               lines researches showed that berberine induces apoptosis in
               leukemic HL-60 cells.

                     2-Veratrum (Hellebore) rhizome

   White Veratrum (European) and Green Veratrum (American)

    Uses
    • Anti-hypertensive.
    • Insecticide due to high toxicity.
    • In veterinary medicine.
    Toxicity symptoms

             Sneezing, runny nose followed by death due to respiratory paralysis

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