Page 100 - MNU-PM502- Pharmaeutical Microbiology Theoritical Book
P. 100
Pharm D- Clinical Pharmacy Program Third Level Pharmaceutical Microbiology& Antimicrobials (PM 502)
First generation
The most commonly used first generation cephalosporins
▪ Cephalexin, Cefadroxil
▪ Cefazolin
➢ Parenteral cefazolin used for
➢ surgical wound prophylaxis
➢ Streptococcal Pharyngitis
Spectrum:
• Active against Gram Positive bacteria (Streptococcus. Staphylococcus)
(Effective alternative to Penicillins)
• Limited activity against Gram-negative bacteria
• Poor activity against Anaerobes
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