Page 105 - MNU-PM502- Pharmaeutical Microbiology Theoritical Book
P. 105
Pharm D- Clinical Pharmacy Program Third Level Pharmaceutical Microbiology& Antimicrobials (PM 502)
4- Monobactams
Aztreonam G -ve bacteria
➢ only against Gram-negative bacteria
(Enterobacteriaceae and Pseudomonas).
➢ NO ACTIVITY against Gram positive and anaerobic
bacteria
Non-Beta-lactam antibiotics
Glycopeptides Vancomycin, teicoplanin, Telavancin
Vancomycin
Mechanism:
binds to the d-alanyl–d-alanine portion of the peptide side chain of precursor
peptidoglycan subunits, prevent access of
PBPs so, inhibit peptidoglycan synthesis
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