Page 1055 - The Toxicology of Fishes

Index 1035

inhibition concentration (IC), 677 CYP3A in, 172
inhibitory G-protein (G ), 461 cytosol, 203
i
initiation, 535, 536, 537, 539, 544, 563, 566, 568, epoxide hydrolase activity, and, 181
575 heavy metals, and, 407–408
of lipid peroxidation, 292 hypertrophy of, 82
inland silverside (Menidia beryllina) marine test, osmoregulation, and, 406–408
950 P-glycoprotein in, 366
inorganic tin, 503 pH of, 73
iNOS, 276 proximal, 74
inositol triphosphate (IP ), 463 retinoid levels in, 696
3
inositol-1,4,5-triphosphate, 463 UGTs in, 188
insecticides, 85, 123, 168, 213, 214, 299, 305, intracellular fluid, 60
477, 625, 735, 742, 824 intrahepatic bile passageways (IHBPs), 337
carbamate, 431, 432, 433–434 intrahepatic biliary system, 335
chlorinated hydrocarbon, 806 intramuscular injection, 78
cyclodiene, 428, 437, 438, 439, 445 intraperitoneal cavity, 78
feeding rates, and, 428 intraperitoneal injection, 78, 91, 500, 502, 507,
lipophilic organochlorine, 80 508, 509, 511
organochlorine, 437–439, 504, 506–507, 808 intravascular injection, 98–99, 103–105, 124–126
organophosphorus, 431, 432, 433–434, intrinsic hepatic clearance, 93, 121
504–505 invertebrates, benthic, see benthic invertebrates
particulate matter, and, 809, 810 inverted repeats (IRx), 353
predator–prey interactions, and, 428 iodide, 477
pyrethroid, 428, 434–437, 444, 445, 609, iodine, 476
742, 744 ion channels, 424, 425, 426, 427, 429, 440, 444,
synthetic, 805–815 601, 604
pyridaben, 744 ion gradients, 401, 425
resistsance to, 621 transmembrane, 63
thyroid, and, 477 ion regulation, 69, 401, 405, 406
insulin, GSTP and, 197 ion transport
insulin-like growth factors (IGFs), 460, 461, 702, calmodulin-dependent, 409
900 disturbance of, 403–405
int, 557 ion trapping, 61–62
interferon, 493 ionization, 61
interleukin 1 (IL-1), 288 ions, 401–410, 425, 441
interleukin 1β (IL-1β), 494 iron, 37, 91, 275, 276, 277, 278, 285, 287, 288,
interleukin 2 (IL-2), 494 292, 296, 298, 300, 930
interleukin 8 (IL-8), 288, 899 transport, 63
interleukins, 493–494 iron superoxide dismutase (FeSOD), 279, 300
International Programme on Chemical Safety ischemia-reperfusion tissue injury, 295
(IPCS), 767 isoenzymes, 158, 185, 186, 351, 352, 576
intersexuality, 711, 971–972, 976–982, 983, 986, antioxidant, 302
987; see also feminization, masculinization isoforms, 191, 493
interstitial cells, 460 isomerization, 460
interstitial fluid, 60, 78 isomers, 506–507
intestinal length, 69 isozymes, 162, 164, 168, 183, 193, 202, 203, 205,
intestinal lumen, 69, 71, 83, 343, 347 211, 212, 350, 541, 542
intestine, 63, 69, 72, 78, 115, 117, 166, 167, 174, iteroparous fish, 82
188, 200, 365, 401, 606, 692, 797
ACTH, and, 410 J
biotransformation in, 209 Jackfish Bay, 957
blood flow in, 78–79 Japanese eel (Anguilla japonica), 361
CYP2P in, 168 nephroblastomas in, 560