Page 1087 - The Toxicology of Fishes

Index 1067

animal use in, 6 transport, carrier-mediated, 63
basic concepts of, 663–664 transport pathways, 10, 14, 17, 57, 60, 132
chronic, 676–677, 949–950 transporter complement, 71
criteria for, 669–672 transporters, 362
design of, 672–673 ATP-dependent, 362
early life stage, 662 hepatocytic, 361
mesocosm, 734 treated sewage effluents, 6, 440
microcosm, 671, 734 antiandrogenic, 992
objectives of, 660–662 estrogenic effects on fish in English rivers,
organisms used, 673–674 971–995
pyrethroid, 807 estrogenic substances in, 982–985
single-species, 670–671, 734, 735, 743, 745, gonadal duct development, and, 980
746, 747 impact of, 974
standard procedures for, 674–675 intersexuality, and, 980
subchronic, 662 male gametes, and, 982
sublethal, 949, 950, 954 removal of edocrine-disrupting chemicals
tiers of, 736 from, 995
types of, 662–663 steroid estrogens in, 985, 992
toxicodynamics, pyrethroid, 812–814 T-reg cells, 567
toxicokinetics, 55–134, 440 tremors, 430, 432, 436, 437, 439, 808
defined, 56 trenbolone, 470
modeling, 91–126 triacylglycerols, 359
pyrethroid, 810–812 trialkyltin, 35
toxicology tributyltin, 11, 115, 199, 208, 503–504
biomedical vs. environmental, 3 tributyltin oxide, 442–443
comparative, 237–239 tricaine methane sulfonate (MS 222), 78, 182, 206
developmental, 250 trichloroethylene (TCE), 568
environmental, 758–760 trichloromethyl radical, 296
research, 237 2,4,5-trichlorophenol, 27
synthetic pyrethroid insecticides, 805–815 2,4,6-trichlorophenol, 27
TPA response element (TRE), 288 2,4,5-trichlorophenoxyacetic acid (2,4,5-T), 206
trace amine-associated receptors (TAARs), 258 2,4,5-trichlorophenoxyacetyltaurine, 206
trace elements, 19 1,2,3-trichloropropane, 571
trace metals, 699 trichlorphon, 504
transcription, 472, 558, 559 Trichogaster trichopterus, 503
activation, 353 triclopyr, 206
transcription factors, 237, 258, 287, 288, 353, 357, triethylene glycol (TEG), 673
358, 464, 558–559, 827, 828, 833, 834 triethyltin, 441
antioxidant response element, 288, 290 3-trifluoromethyl-4-aminophenol, 179
ligand-activated, 463 3-trifluoromethyl-4-nitrophenol, 179, 352, 823
reactive oxygen species, and, 287 trifluralin, 81
transferases, 279–280 triglycerides, 358
transferrins, 80, 494 17,20β, 21-trihydroxy-4-pregnen-3-one (20β-S),
transformation, 647 461, 465, 473, 474
receptor, 244 triiodothyronine (T ), 186, 201, 476, 477, 900
3
transforming growth factor (TGF), 493, 494 trimethylamine N-oxide (TMAO), 177
transforming growth factor α (TGF-α), 472, 495 trimethylamine oxidase, 175
transforming growth factor β (TGF-β), 494 bis(tri-n-butyltin)oxide (TBTO), 504
transgenesis, 237 trinitrophenylated lipopolysaccharide (TNP-LPS),
transgenics, 251 898
transition metals, 275, 276, 285, 292, 293 tripeptides, 476
transmembrane transporters, 359 triphenyltin, 199
transport associated protein 1 (TAP1), 899 tritium-labeled ligands, 247