Page 532 - Veterinary Toxicology, Basic and Clinical Principles, 3rd Edition
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Organophosphates and Carbamates Chapter | 37  499




  VetBooks.ir  TABLE 37.2 (Continued)


                              Chemical Name
                                                                                Oral LD 50 in
                                                                       Mol. wt.
               Chemical
                                                                                               rabbit (mg/kg)
                                                                                Rat (mg/kg)    Dermal LD 50 in
               Dicrotophos    (1E)-3-(dimethylamino)-1-methyl-3-oxoprop-1-en-1-yl  237.19  22  223
                              dimethyl phosphate
               Dimethoate     O,O-dimethyl S-[2-(methylamino)-2-oxoethyl]  229.26  250         400
                              dithiophosphate
               Disulfoton     O,O-diethyl S-[2-(ethylthio)ethyl] dithiophosphate  274.40  2    6
               Ethion         O,O,O ,O -tetraethyl S,S -methylene bis  384.48   27             915
                                     0
                                   0
                                               0
                              (dithiophosphate)
               Famphur        O-{4-[(dimethylamino)sulfonyl]phenyl} O,O-dimethyl  325.34  35   2730
                              thiophosphate
               Fenamiphos     ethyl 3-methyl-4-(methylthio)phenyl      303.36   15.3
                              isopropylamidophosphate
               Fenitrothion   O,O-dimethyl O-(3-methyl-4-nitrophenyl)  277.23   250            1300
                              thiophosphate
               Fenthion       O,O-dimethyl O-[3-methyl-4-(methylthio)phenyl]  278.33  255      330
                              thiophosphate
               Fonofos        O-ethyl S-phenyl ethylphosphonodithioate  246.33  8              25
               Glyphosate     N-(phosphonomethyl)-glycine              169.07   4300           .5000
               Gluphosinate   2-amino-4-[hydroxy(methyl)phosphoryl]butanoic acid  198.16  2000  .4000
               ammonium       ammoniate
               Glyphosine     N,N-bis(phosphonomethyl)glycine          263.08   3925           .5010
               Isazophos      O-(5-chloro-1-isopropyl-1H-1,2,4-triazol-3-yl) O,O-  313.75  40  .3100
                              diethyl thiophosphate
               Isofenphos     isopropyl 2-{[ethoxy(isopropylamino)     345.40   32             162
                              phosphorothioyl]oxy}benzoate
               Malathion      diethyl 2-[(dimethoxyphosphorothioyl)thio] succinate  330.36  885  4000
               Methamidophos  O,S-dimethyl amidothiophosphate          141.13   13             110
               Methidathion   S-[(5-methoxy-2-oxo-1,3,4-thiadiazol-3(2H)-yl)  302.33  25       200
                              methyl] O,O-dimethyl dithiophosphate
               Methyl parathion  O,O-dimethyl O-(4-nitrophenyl) thiophosphate  263.21  9       63
               Mevinphos      methyl (2E)-3-[(dimethoxyphosphoryl)oxy]but-2-  224.15  3        16
                              enoate
               Monocrotophos  dimethyl (1E)-1-methyl-3-(methylamino)-3-oxoprop-  223.16  8     354
                              1-en-1-yl phosphate
               Omethoate      O,O-dimethyl S-[2-(methylamino)-2-oxoethyl]  213.19  50          1400
                              thiophosphate
               Paraoxon       diethyl 4-nitrophenyl phosphate          275.19   1.8
               Parathion      O,O-diethyl O-(4-nitrophenyl) thiophosphate  291.26  3           6.8
               Phenthoate     ethyl [(dimethoxyphosphorothioyl)thio] (phenyl)  320.36  200     4000
                              acetate
               Phorate        O,O-diethyl S-[(ethylthio)methyl] dithiophosphate  260.38  1.6   2.5
               Phosmet        S-[(1,3-dioxo-1,3-dihydro-2H-iso-indol-2-yl)methyl]  317.32  147  3160
                              O,O-dimethyl dithiophosphate
               Phosphamidon   (1Z)-2-chloro-3-(diethylamino)-1-methyl-3-oxoprop-  299.69  15   125
                              1-en-1-yl dimethyl phosphate

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